can someone explain these?

Months
Slope Log (PSA) 0.48
Doubling Time 1.44 months
Velocity 15.44 ng/ml/mo
Years
Slope Log (PSA) 5.77
Doubling Time 0.12 years
Velocity 185.28 ng/ml/yr
i do not know what any of this means can someone explain please
ty
cc

cc,
I think this may be what it all means:
The "slope log" would be a graphical representation of the PSA velocity.
The Slope is arrived at thus:
Your PSA increased by 15.44 ng/ml over a month (say 31 days) so the slope of your PSA increase would be 15.44 divided by 31 days = 0.49
This can be plotted on a graph to ascertain your expected PSA at some future date
Doubling time is the amount of time it takes for your PSA to double (in this case 1.44 months)
PSA velocity is the speed at which your PSA increases per month

The second portion is the same thing only expressed in terms of a year rather than a month

Bill

Post Edited (BillyMac) : 7/3/2012 11:42:14 PM (GMT-6)

Actually, I wasn't using all of the information. With the annual velocity, it says that your current PSA is about 0.57 (am I close?).
With a doubling time of 1.44 months, that translates into 8.33 doubling times in one year.

Based on this, in about 43 days, it will rise to 1.14. In about 86 days, it will rise to 2.28. In about 129 days, to 4.56, and every 43 days therafter will double. At about 300 days, it will be up to about 73, and so on.

Keep in mind that this assumes that the doubling time stays the same, and that you do nothing to prevent the progression. There are lots of treatments these days that will completely change these statistics, not the least of which is HT, which can turn the PSA on a downward curve rather than a geometric increase (which is what the statistics claim it will do).
Jeff

His psa is now 81 it was 78 his psa test are done every 3 weeks they consider this stabilized psa . Thank you all for explaining i think i get the gist of it now lol:) the reason I asked was I did the Sloan and Kettering prediction tool Prostate Cancer Nomogramsn i called our care manager and asked if it was accurate and she said yes but with him going in to the mdv3100 trial to add 3 months to it although it is not the same one our onc uses it is the same results of 12 months 9 months with out treatment but to understand that not everyone is the same but from my husbands bad response to past chemo drugs it is probable that the 12 months is fairly accurate. we have also had to take into account his weight loss his loss of muscle mass and his just plain tired of treatment and his lack of appetite and his desire not to take anything to stimulate his appetite we have discussed this over the last few days and he says he is fine with it he has no desire to change the outcome of this or to try that once the mdv3100 stops working he will not be doing anything else it is really sad but i do understand after 4 years he is just tired and I respect that he will be going for quality over quantity and I guess it is about time he did and do somethings he has been to sick to do
Thank you all for everything I will be still posting results of mdv3100 trial as we go along
I wish everyone the very best and pray for all of you that a cure is found soon
best wishes and low psa
C.C.