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PSA up again..Frustrated

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Posted 10/16/2012 12:23 AM (GMT 0)
4.12...4.61...3.95...6.18...4.64...4.33...4.89...5.72...5.00...4.90..and now 5.68. If the uro suggests a third biopsy what do I do??? I have been taking PSA tests for 3 and a half years and two negative biopsies. The 4.90 reading in June 2012 is only up .30 from the test in Oct 2009. With the swings in PSA  I am thinking of suggesting another test in November and a second in February to see if it stays above 5. At least then it will be justifiable in my mind. I am not worried about having advanced PC so I can handle the wait. I see my uro next Monday. Your thougts my friends??? Greg
Posted 10/16/2012 12:25 AM (GMT 0)
it might be a nuisance, but let's face it, things could be a whole lot worse. Keep monitoring closely.
Posted 10/16/2012 12:49 AM (GMT 0)
Any history of PCa in your family?   Have there been any other abnormal findings on previous exams?  Has your doctor put you on an antibiotic regimen to rule out a chronic prostate infection?

Depending on other indicators in your case, maybe it's time for a "saturation biopsy."   A prostate saturation biopsy typically entails 40-80 core samples taken from the prostate under general anesthesia. This technique is used on certain high risk patients, typically with elevated prostate specific antigen levels, abnormal findings on previous biopsies, or abnormal rectal exams.

Just a thought.  I am by no means a doctor.  

Posted 10/16/2012 12:54 AM (GMT 0)
Sorry to hear the news.

On my 2nd of 3 biopsies, I had a lot of PIN that had changed to HGPIN. By the 3rd biopsy, the HGPIN
had turned to cancer. So sounds like you will always need close monitoring, as its possible at some point your HGPIN cells may turn to cancer. For your sake, I hope not.

David
Posted 10/16/2012 1:21 AM (GMT 0)
I would go for a color doppler ultrasound. But of course I would say that. That's what I did.

Robert
Posted 10/16/2012 11:27 AM (GMT 0)

John T said...
Greg,
I think I hold the biopsy record for 13, and it wan't for a color doppler ultrasound I would have had at least 5 or 6 more before they found it. For piece of mind I would get a color doppler ulltra sound targeted biopsy from a known expert for your next biopsy. It would be worth the travel to see Duke Bahn in Ventura Ca or Fred Lee in Rochester Mi.

I think this advise from John T is still your best bet. Good Luck.
Posted 10/16/2012 2:28 PM (GMT 0)
The trans-rectal biopsy procedure can not reach some areas of the prostate gland..The "saturation biopsy" can..Also, when guided by a color-Doppler ultrasound machine the Urologist gets a better picture of what he is looking for..

So if you have that third biopsy, try to have a more effective one performed...I went through this same nightmare and my cancer was well advanced before they found it...
Posted 10/16/2012 3:21 PM (GMT 0)
By my signature you'll see that they found my cancer on the third biopsy ... Dx at G8 (downgraded to G7 after RALP).

I have no doubt that it was there on my first and second biopsy, but they didn't hit it. Wish they had. I might not have had to have the nerves removed from one side.

No question in my mind. I'd say do it now.
Posted 10/16/2012 4:23 PM (GMT 0)
Have you had a free PSA test and a PCa-3 test done? Those could help you and your doc decide what to do next?
Posted 10/22/2012 10:51 AM (GMT 0)
Greg,
Your stats are very similar to mine. While I hate the fact that I have this crap at age 47, I am thankful that I know and am dealing with it.
In my opinion you need to stay after it. If you can I would seek out one of those facilities that offer the color Doppler as John T suggested. You can also add Dattoli in Sarasota Florida to those facilities. You should also give some serious thought to the saturation biopsy. It is a more complete procedure than the standard TRUS biopsy.
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