I had just filled an Rx for a simple antibiotic, and it was up from $8 for 60 to $122 for 60.
Looking at the site where they track this sort of thing, trying to figure out what was happening, I also saw a couple of the ingredients of Trimix are in very limited supply, so if you are refilling a prescription, be sure to ask what your co-pay is, lest you break the bank. I have not had mine filled since the end of December, and the shortages seem to have started in January, so don't have a first-hand story on Trimix. Beware.