Trimix questions

Welcome aboard!

You'll get some replies from those who are on Trimix. I am on straight Alprostadil (PGE-1) so also doing injections.

My first two questions would be: (1) Did your husband's uro give an upper limit or ask him to check in if he wanted to raise the dosage? (2) Have you tried, at all, to go above the .10?

Seems to me you might want to bump up the dosage and see if that produces better results. My uro started me at .15 ml with instructions to titrate (adjust) until I found a dosage that worked well for me. The objective was to reach something along the line of 6 out of 10 on a firmness scale (enough for penetration) and something that lasted about an hour. I went as high as .27 in testing but actually settled in at .22. At lower dosages, I either did not get hard enough or did not last long enough. I have great rigidity (9-10) for as long as I need right now.

On location, I aim for about one-third of the way up from the base, at between the 1:00 and 3:00 position, and alternate sides each time. I use a 1 ml 5/16" 31-gauge insulin syringe for delivery.

Just to note, with the injections, the shaft will harden as the cavernosa fill up but the head of the penis may not engorge like with natural erections. Still should not have the "hinge" effect.

Others have experienced the issue of losing an erection when lying down and find the vertical position is better. There are discussion threads on here about it but others can give you some feedback in this thread.

There are guys on here who have used way more than the .10 you all are using. It certainly is not "one size fits all" when it comes to injections. The one thing you want to avoid is getting too high a dosage and ending up with priapism where there is an ER visit.

Congratulations on the good PSA numbers and good luck with getting the injection stuff worked out.

..

3.5 months out might be a bit early, you are not healed up quite yet, but, you may want to try different formulas of the three ingriedients, your uro or pharmacist can help with formulas.

Thanks guys!

His cocktail (sorry) is:

C-Papaverine: 18mg

Phentolamine: 1mg

PGE1: 8/5mg

First injection at docs office was .05.  He has titrated it up to the .1.   Doc is very pro-rehab so I'm sure he'll call if we continue to have some issues.  I wonder if going up just 1 line on the syringe is enough.  I'm thinking maybe he should up it to .13, the .15. 

We are more intrigued and curious when it doesn't work great.   We are secure enough not to get frustrated, etc though we want to make every one count since we can only do 3 per week.  

I believe we are getting the location right.  He pumped yesterday and said it was easier to inject after pumping. 

I know it's still very soon, but everything is going so well with is recovery, this is really the only issue left to work on.  And we like that kind of work!

Interesting comment that the head may not get as hard as the rest.  That was very noticeable to me yesterday. 

As a former music teacher, I know that the only way to get into Carnegie Hall is Practice, Practice, Practice!  So we'll practice!

I really appreciate you taking the time to reply.

 

azsunshine,

The improvement with upright posture indicates venous leak. Has he tried a constriction band?
Cheap, simple and effective:

www.amazon.com/gp/product/B000RY5QVW/ref=oh_details_o05_s00_i00?ie=UTF8&psc=1

Also, I found it very interesting in the Mulhall talk you posed a while back when he said that 3-4 months post-op is often the low point for potency as the peek of bruising, inflammation and scaring around the nerves lags surgery by that much time. That may be part of what is going on as well (i.e. earlier he may have had more nerve function working synergisticaly with the trimix and now that has tapered off so more trimix is needed).

Some of the information you are asking for about trimix strengths is in a thread I started about a year ago when I had received a scrip from my doctor with no instructions at all. He usually gives out an information sheet with the scrip. It instructs the patient to make an appointment to come back with his drugs to be shown how to use them. I had taken my wife with me on the appointment where I asked for the trimix scrip. This is usually a good idea, as she has a good memory and it keeps her in the loop, but she does tend to chatter when she gets nervous and the doctor is a friend of hers. Somehow the info sheet got forgotten and I assumed the doctor thought it was so all self-evident that I would figure it out. I did, actually. The shot I got in my doctors office was my third. He accused me of ignoring his instructions but, in point of fact, he forgot to give them to me.

I will admit that I was nervous about making up my own dosages (among other things) but I was looking at my first Lupron shot which would start two years of ADT and I was grimly determined to start my rehab while I still remembered why that was a good idea.

Note to you kids at home: be sure to ask your doctor for instructions when you start your penile rehab and follow those instructions carefully. PeterDA was a nervous wreck at the time and not making very good decisions...

That's the ring that flew across the bed.  We've tried the others and didn't like those either. 

Ok, success with .15 today!  BIG success.  Erection lasted about 1½ hours so not too long.  We are SMILING!