On things to do becoming monumental tasks and opportunistic infection

I would very much doubt if your symptoms are from your low grade PC. Most PC is symptomless until it is really advanced. I would suggest checking other causes.

Its the stress from the diagnosis and dilemma, you sense. Your mind is on everything that can go worn wrong and not on all the things that will go right. Once you make a call and do it, You will feel better. and yes these are things that go with Pca, for some. sounds like As would be hard on you, so probably should opt for treatment , but surgery may not be the answer. Check BT, In, out done, less chance of long lasting S/E's. I think you should try AS, if you think you can rise above your fears. Yours sounds like a classic case of fear trumping your mind. Good luck, this is not gonna kill you, stress can.

RobertT –

For some curious reason there are at least a couple of other threads running right now here on the forum about the relationship between PCa and depression. A subject on the minds of a number of people right now, I guess.

Those who have commented so far are correct that it is highly unlikely that a PCa of the level that you describe (G6, only 5% and 10% in two cores) would be causing you any symptoms of any kind. And there is evidence that it is also highly unlikely that a cancer of that level is ever going to develop to the point that it will someday become lethal for you. You should put those worries aside.

But as the others have said, it seems very likely that what you have developed is a significant case of depression, and that is what is producing the symptoms you describe, such as extreme fatigue. And since you, as you say, have never taken meds for mental health issues, nor seen anyone for them, you may have no experience in recognizing a severe case of depression such as you probably have, and you are thus left confused as to what is causing your symptoms.

I agree with the others, that you need to admit these symptoms to your physician, and be prepared to follow his/her advice on how to combat them. Really, medications and counseling can make a big difference, and certainly could in your case.

One more comment on the statement that was made in your post that symptoms such as you described can be "stress related and thrive when defenses are down." In April of 2011 my dear wife of 39 years died suddenly and unexpectedly of a cardiac arrest, leaving me a devastated widower. Then the ongoing incredible grief and stress level that I experienced over the next two months (at least) was so utterly overwhelming for me, that I think something stress-related happened. In June, just about two months later, I began experiencing the chain of events, namely BPH, a TURP, and eventually a PCa diagnosis in December of that year, that brought me to where I am today.

My point in relating this: I've given it much thought, and I have entirely come to believe that the truly colossal stress and depression that came over me at the death of my wife in April of that year so suppressed my immune system, so drastically, that the BPH and PCa (which granted had probably been developing in me for some time) "saw their chance" as it were, and suddenly developed quickly and in earnest, and became serious and very obvious, just a couple of months into this severe immune system suppression caused by the death of my wife. Absent the extreme stress, perhaps these physical events would have continued to be held in check, or at least delayed, and it was the "stress crisis" of her passing that brought them out.

I ran this theory past my uro, and I'm afraid he was a bit skeptical about it all, but I still remain convinced that severe depression of one's immune system, as happened with me, can "let loose" all kinds of things that had previously been held in check, even "bottled up" as it were, causing a host of symptoms that can cause fear and concern.

Consider that this may have happened to you, as you have experienced as well a severe psychological trauma upon diagnosis that may have led to your symptoms. In any case, it's a much more likely scenario than your G6 cancer causing anything.

Ask your doc to test your vitamin D and iron levels. Either of these being low could contribute to your fatigue and low energy levels. Even a low normal Vitamin D level can give many people symptoms.

For some reason low Vitamin D and prostate cancer seem to be connected but I am starting to wonder lately if very low D levels are just becoming commonplace due to our indoor lives now.

I guess what I am trying to say is it might be something else causing these symptoms and not the cancer and I would start there to try rule things out.