Taxotere for Early Stage High Risk PCa

RP April2014
Pathology; GS4+4, 152 gr, Neg Margins ECE+ SVI- LN- Vasc-
My post RP PSA at 6 months = 0.224 and 9 months 0.29
PSADT is 8.7 months

I was ECE for 2 years or more before surgery.
With a GS4+4 I think I am systemic and that SRT is not a viable option

So ..................
Facts
HT can weaken but does not kill all PCa cells
Otherwise HT could provide a cure for systemic disease

SRT can only kill in the Prostate bed and surroundings
One strategic camp says "Hit early, Hit hard"
But SRT + HT will not cure if the PCa is systemic

However ....
Taxotere is used to kill PCa cells in the later stages of disease
when HT fails and the PSA levels are high and tumors are large

So my idea
Why not use Taxotere to kill and provide a likely cure
for systemic disease in the EARLY stages when PSA levels
are low and tumors are tiny ?

Is there some reason this is not possible or that no
doctor will go along with it ?

Why has this not been offered as a standard option
for early high risk disease ?

I am willing to walk thru hell if it will give me a cure.
===============================
2000 1st PSA 12
Antibiotics then biopsy
Size is 4x, no PCa
Live with symptoms slowly getting worse
2007 1st AUR, ER visit PSA 14
2011 April 2 AUR, ER visits in one week
2011 April TURP Pathology No PCa
I thought PCa free Did not do DRE for 3 yrs, Sigh :-((
PSA was steady at 14; Free PSA to Bound PSA 37%
Both markers lied to me !
2014 Jan blood in urine DRE shows poss T4 PCa
Biopsy 7 cores right side all 50% PCa GS 3+4
2014 Feb Fly to NYC MSKCC
Bone scan neg MRI shows ECE
Biopsy slides reevaluation at 7 cores all 80% PCa
GS 4+3 upgraded, both lobes involved
Pre Op PSA 19
2014 3 April open RP
Pathology; ECE+ LN- SV- Vasc - 152gms
Neg Margins, PNI + , half nerve taken one side
GS upgraded to 4+4 Grading pT3aN0MX
ED , Incont down to 1pad/day in 5 months
July 3mo Post OP PSA 0.224
August 4mo Post OP PSA 0.247
October 6mo Post OP PSA 0.29
PSADT 8.7 mo w MSKCC Nomogram

Post Edited (pablocito) : 12/3/2014 7:16:36 PM (GMT-7)

Hello !

I am in the very first wave of prostate cancer patients that are being treated with the new protocol of adding chemotherapy (Taxotere) to A.D.T. (Lupron hormone shots) after being diagnosed with advanced prostate cancer.

I was diagnosed a year ago with a PSA of over 100, and multiple cancerous nodules that were found in both of my lungs. The Lupron shots cleared up all the lung nodules within a few months and also brought my PSA levels down to a relatively low level. Since then, I have recently undergone the standard six rounds of chemotherapy (Taxotere) treatments, given three weeks apart, over a total of eighteen weeks. My side effects from the chemotherapy treatments were relatively mild, for which I was thankful. I realize each patient is different and has to make their own decision about chemotherapy. Side effects can greatly vary from one patient to another.

I do think it's important to let others know that the chemotherapy treatments brought my PSA down even lower than the initial Lupron hormone treatment shots. My current PSA is now less than 0.10, which is far less than the initial PSA which stood at over 100 when all of this began over a year ago.

It's important to note that I am now under the care of both an oncologist and my original urologist. In my personal opinion, it's important to get an oncologist on your team early in the game, if you are diagnosed with advanced prostate cancer. I had to ask my urologist for a referral, so that an oncologist could be added to my medical team for the chemotherapy part of my treatment. Be proactive and ask directly for a referral so that you can consult with an oncologist, if you have advanced prostate cancer. I hope that my story can help someone else out there.

Keep fighting the good fight !
Cyclone