PSA down to 1.2 from 209 in one month after start of ADT

Hi Folks:

I have not posted here for a while but have been checking in daily.

Well, lots has happened to me since my initial DX with a PSA of over 209 last November.

I started ADT on December 4, 2014 and had my first PSA and T draw on January 5th. The results came in at PSA down to 1.2 and T rate to 63...Not thrilled about the T and need to get it below 50 but I will take a 200+ drop in PSA in one month all day long.

Hope for even lower numbers on my next draw March 2nd

Hope you are all well

geop

Thanks...Time will tell

I had a heck of a time with doctors in private clinics and finally decided to go to Moffit Cancer Center in Tampa, FL. Dr. which is similar to Mayo etc.

Dr. Jingsong Zhang there was very pleased with my results and is running another blood test to determine if I should initiate early chemo with HT. My gut tells me to hit hard and heavy with chemo also while it still seems to be HT naïve.

I honestly expected a drop after the initiation of HT but not 208 points at this stage.

Now I have to work on getting T rate down and somehow I suspect that it has gone down to castrate levels by now as the fatigue is setting in periodically and my half ass libido from a few weeks ago while still above castrate levels is now zilcho. I would rather hang with you guys drinking beer then making love to a beautiful babe.

If my next PSA shows another drop, the Doctor will do another bone scan to determine if the bone mets are resolving.

BTW, I was overly impressed with Moffit Cancer Center vs. some of the other local cancer centers here in Tampa Bay (don't want to mention names)

Great news Geop! I would imagine the HT is shrinking your mets quite nicely with a PSA drop like that! Tough call when to add chemo, best of luck!

Cheers, Doug

Fantastic drop, Geop!

I agree that chemo now is likely to give the best results, especially with your multiple mets.

If your T doesn't come down below 50 eventually, maybe talk to your oncologist about adding Avodart - at least that will prevent the residual T from getting metabolized into DHT, a more powerful androgen receptor activator. Zytiga (or an older drug, ketoconazole) may get rid of the adrenal sources, but it will be hard to get before castration-resistance is diagnosed. The other thing you can try is estrogen patches. There is another drug called Capesaris (GTX-758) that is in clinical trials right now in FL, but it also requires castrate resistance.

Please keep us in the loop.

- Allen

Geop, congratulations on the quick PSA drop

Love reading success stories like this.
Hope it drops further soon and you have much success