Getting Trimix dose right

Hi, My husband at first used trimix 15 units with not good results..now uses super quad only 3 units and is maintaining for about 15-20 minutes...we are still learning the magic amount. It is so tricky to find the right amount...I think I would definitely would speak to your ED dr. Never give up...

I was pretty much in the same boat. My URO changed the formula to a weaker one so that I could inject more.

This is a very important question, and I think that all men need to understand the answer.

I'm not doctor, but I am absolutely certain that I can tell you what is happening here... because something very similar happened to me too.

Let's look at the facts:
1) Using the exact same amount of trimix, sometimes no erection and other times it lasts for hours. Clearly, the trimix itself isn't the problem since that variable is held constant.
2) I assume that your husband is injecting correctly each time, so the delivery of the timix is also a variable that is held constant.
So, it must be something else that is changing.

I'll tell you exactly what is changing: his adrenaline. Anxiety causes adrenaline. Adrenaline is the most powerful anti-erection chemical in the world. So, the more your husband feels stress about his inability to get erections, the more adrenaline his body will produce, which undermines his ability to have (or keep) an erection.

The exact same thing happened to me. Dr. John Mulhall (world famous ED doctor at Sloan Kettering; see link in my signature below) explained the whole adrenaline thing to me. He told me to relax and not worry about the trimix outcome so much. He suggested getting a rubber ring ("¢0¢k ring") to help maintain the erection, and after a bit of time my confidence would improve and stress would decrease and then the trimix would work fine every time. He was 100% correct.

Best of luck.

Gedman

If he has erections in his sleep without any trimix at all, that is FANTASTIC news. He may not need trimix at all!

Note that a doc won't give him anti-depressant meds to reduce his erection anxiety, because those same anti-depressant meds also have a strong anti-erection side effect.

Gedman

This is a reply that may apply to many regarding Trimix and Penile injections in general.
My urologist is so busy performing surgeries that most post operative issues are handled by a Nurse Practioner.

Unfortunately, I don’t think she is as knowledgeable as those that are on this forum. I had to ask for Trimix
and she prescribed in the lowest mixture available. I never got any usable erections and was very cautious
Tritrating. Go low, go slow, right. Except I never got anything out of it although petrified of getting a dreaded
4 hour erection. Much anxiety. Finally, I was able to get her to up the strength to a standard dosage
After starting titration all over again, albeit at a lower starting dose; same thing no usable erections.
After two injections, I sought information on this forum, and read from some others that because of venous leakage, that injected Trimix sometimes leaks out before an erection can be induced.

Using a retention ring and plumping up my penis before injection, putting extra tension to the ring,
I injected. I kept a firm clamp at the base for a good 5 minutes. After 5 minutes and lightening
the tension, couple with slow massage I achieved a very strong erection. That continued even after removing the ring. I had injected 2.5 units, which stood out directly from my body. I couldn’t believe it
after a couple months of failures. It took 2 full hours for it to subside. After an hour, I panicked that perhaps I would have a trip to the ER. I did the usual excercise to redirect blood away, and took sudafed.
Luckily it went away after 2 hours. I now back the dose back to 2 and everything working fine.

SOoo, if you are having problems with Trimix, or injectables not working, it may be due to the drugs leaking back into your body. Thanks to this forum (and no thanks to my Urologist Nurse Practioner), it appears my
ED is under control. Good Luck.