Just saw this today on Yahoo Health news:
<hhtp://medicalxpress.com/news/2016-07-unexpected-results-international-phase-iii.html>
Could someone make this link clickable? Thanks
It appears the Phase III trail on advanced castrate resistant- metastasized PC patients produced only very slight improvement of conditions and overall survival.
Moderators-hope it is Ok to post these references:(each is footnoted)
Prior trial results seemed promising, From Wikipedia:
Positive data from clinical trials in 2011 indicate cabozantinib is beneficial in metastatic advanced prostate cancer (castration-resistant prostate cancer). 97% of patients either had stabilization or improvement in bone malignancies. The median time to disease progression was 29 weeks.[14][15]
One US trial reported in May 2011: The best results were seen in patients with liver, prostate, and ovarian cancer: 22 of 29 patients with liver cancer, 71 of 100 patients with prostate cancer, and 32 of 51 with ovarian cancer experienced either partial tumor shrinkage or stable disease. Fifty-nine out of 68 patients who had bone metastases had their metastases shrink or disappear during the trial.[16]
14)"Exelixis drug slows prostate cancer spread in trial". Reuters. 6 June 2011.
15) Cabozantinib (XL184) Phase 2 Data Demonstrate Encouraging Clinical Activity in Patients with Castration-Resistant Prostate Cancer. Feb 2011
16) "Cabozantinib Shrinks Tumors and Bone Metastases in Prostate and Other Cancers". 31 May 2011.
I focus on the line of hope- "The results teach us a lot about
the challenges we still need to overcome on the way to providing better prostate cancer treatments." The way I see it we tried this, will build on this , and something better will be discovered!" Keep the faith!
Dan
Post Edited (Wings of Eagles) : 7/13/2016 9:10:11 AM (GMT-6)