Fat metabolism blocker may help CRPC

RobertC

Veteran Member

Joined : May 2011

Posts : 1336

Posted 5/16/2017 1:06 PM (GMT 0)

Early study shows possibility of combining CPT1A enzyme with Xtandi. In fact, we are already able to block the action of the CPT1A enzyme. The drug ranolazine is a fat oxidation inhibitor that earned FDA approval in 2006 to treat angina.

/www.sciencedaily.com/releases/2017/05/170515125937.htm

Post Edited (RobertC) : 5/16/2017 7:13:05 AM (GMT-6)

Fairwind

Veteran Member

Joined : Jul 2010

Posts : 4107

Posted 5/16/2017 1:36 PM (GMT 0)

Since the drug involved, Ranexa, (Ranolazine) was approved in 2006 for angina and is in fairly wide use today, doctors can prescribe it "off label" to treat other illnesses like CRPC....It's main benefit is that it keeps Xtandi working for a much longer period of time. As a side benefit, it's reasonably priced...

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