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Had Consult today with UC Davis RO

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Prostate Cancer
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Posted 8/22/2018 6:57 PM (GMT 0)
meeting went well and they want to also opine on the pathology so I am having JHU send the slides to them. Ro said that with the #'s I have right now I should start HT and I agree. He said 3 months on Zoladex. then EBRT and a sbrt boost but the boost I have some time to consider while on HT.. what is kind of weird, is the VA choice program will not pay for Zoladex but will let me(for free) go to the URO at VA and give me Lupron.. Is there a huge difference in the 2 drugs or their SE?? thanks Ed
Posted 8/22/2018 8:11 PM (GMT 0)
Here is the conclusion of one study..

CONCLUSIONS:

There were no statistically significant differences in the levels of castration when comparing leuprolide 3.75 mg, leuprolide 7.5 mg, and goserelin 3.6 mg, altogether. When compared in groups of two, there was a statistically significant difference between leuprolide 3.75 mg and leuprolide 7.5 mg, the latter presented better results in reaching castration levels, cutoff ≤ 20 ng/dl. The importance of this difference, however, must be measured with caution, since the comparison of the three groups simultaneously did not reach the established significance level, even though it came close.

The VA usually uses Eligard, same drug as Lupron but with a different time release agent..With these drugs, doctors sometimes recommend to one that generates the best $$. What the VA pays for its drugs is unfortunately not common knowledge..
Posted 8/23/2018 3:04 AM (GMT 0)

Fairwind said...
Here is the conclusion of one study..

CONCLUSIONS:

There were no statistically significant differences in the levels of castration when comparing leuprolide 3.75 mg, leuprolide 7.5 mg, and goserelin 3.6 mg, altogether. When compared in groups of two, there was a statistically significant difference between leuprolide 3.75 mg and leuprolide 7.5 mg, the latter presented better results in reaching castration levels, cutoff ≤ 20 ng/dl. The importance of this difference, however, must be measured with caution, since the comparison of the three groups simultaneously did not reach the established significance level, even though it came close.

The VA usually uses Eligard, same drug as Lupron but with a different time release agent..With these drugs, doctors sometimes recommend to one that generates the best $$. What the VA pays for its drugs is unfortunately not common knowledge..

Thanks for that FW.. my biggest interest between them are SE's.. any insight on that? thanks. Ed
Posted 8/23/2018 10:26 AM (GMT 0)
SE will be the same. The side effect from the drug is ultra low T. The side effects from ultra low T are as we have often discussed. hot flashes, low energy, weight gain, etc. doesn’t really matter which drug you choose.
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