ADT and elevated glucose/lipid levels

I blame all bad things on PC.

Makes life easier ...

My lipids have been off since being on ADT and my pulse is always elevated (90's). I figure I'll give the Lupron another year to wear off, THEN I'll start to worry if things don't stabilize.

My biggest question is, how much will my PSA increase after ADT, and secondly, how much T will recover? See you in a couple of weeks!

Rich, I was warned about a potential uptick of triglycerides, cholesterol and glucose levels due to ADT.

Mine were low before ADT, and triglycerides and cholesterol were up slightly, but still not out of normal range. Glucose up to borderline, but not alarming. I like sweets Doc says they'll come down as ADT wears off...we'll see.

Do not give up drinking...or desserts! Life is too short for those draconian measures.

Safe travels.....See you on the 28th!

GoBucks said...

Saipan Paradise said...
The trip to Florida will cut my alcohol consumption severely, as I'll be with family most of the time and none of them drink.

Maybe you should hang with the "boys" for more than 1 lunch?

Believe me, that thought has crossed my mind repeatedly.

For a real eye - opener, get all of your pituitary hormone levels charted out before you start Lupron or Eligard or Firmagon or any other luprolide - related chems, then get them checked again while you are on the chems. I did that, and it has given me the rather (more) serious view of those chems that I currently have.

Look - what the doc is focused on is what he/she intends the treatment to do. They want to deprive the PCa of testosterone, which is a hormone, so they call the therapy "hormone therapy". The drugs stop testosterone production in the testes via depriving them of gonadotrophin (a pituitary hormone). This is accomplished by having a chemical constantly present in your blood stream that jams your hypothalamus up completely so it jams up/shuts down your pituitary gland completely. So what?

"The hypothalamus plays a significant role in the endocrine system. It is responsible for maintaining your body’s internal balance, which is known as homeostasis. To do this, the hypothalamus helps stimulate or inhibit many of your body’s key processes, including:

Heart rate and blood pressure
Body temperature
Fluid and electrolyte balance, including thirst
Appetite and body weight
Glandular secretions of the stomach and intestines
Production of substances that influence the pituitary gland to release hormones
Sleep cycles

The hypothalamus is involved in many functions of the autonomic nervous system, as it receives information from nearly all parts of the nervous system. As such, it is considered the link between the nervous system and the endocrine system. "

"it not only controls the actions of the pituitary but it secretes at least nine hormones to the pituitary's seven."

linkie - poo:
https://www.visiblebody.com/blog/endocrine-system-hypothalamus-and-pituitary

The effects of this on the human body are profound. In some ways it is like hunting sparrows with a 12 gauge pump shotgun. It works, but kinda makes a mess while doing so. Yeah, these chems are the front line defense against the foe at this time and they do work...for a while.

I call it kicking the can down the road though.

Pratoman said...
Since adt I haven’t been walking or doing much of any cardio type exercise due to a bad knee, so maybe that’s a cause.

Slightly OT, but for the past decade I've had a hard time getting ppl to understand what it's like to have had a complete meniscectomy... total removal of the meniscus in the knee, as a result of my leg being crushed by a truck.

Most people have some knowledge of some arthroscopic repair of the meniscus and assume that every knee problem is repairable. They have no idea what it is like to have bone on bone... not just a degenerative knee, but one that has been pieced back together with a few dozen different fractures and no cushion whatsoever. It is what's known as a Schatzker type 6 tibia plateau fracture.

Whenever anyone tells me that I need to get out and walk more, I just have to grimace. I am fortunate to still have two legs and as of just a few years ago, being able to walk short distances unaided. Counting the years til I will no longer be able to do so, following my surgeon's advice to "baby" my leg and hoping that a better artificial knee will be developed by the time that I will no longer be able to avoid it.

That's one surgery that I fully intend to put off as long as possible.

When my brother in law started taking a statin he described it as he "went to the doctor healthy and came out sick".

What garyi says is so true. As a pharmacist, I have wailed about the same thing. Evaluating drug-drug interactions oversimplifies the potential interactions of polypharmacy. There are few studies on drug-drug-drug-drug interactions. When we put patients on 15 meds for 5 different problems in isolation, we are asking for unknown complications. The following is not true for all by any means.....but most physicians have forgotten how to evaluate total care for patients and are more likely to just write more prescriptions.

Paul