Poor bioavailability is the major hurdle in getting in vivo results to match the often excellent resuts in vitro results seen in the lab, when a substance is put in direct contact with PCa cells. The "gold standard" there is observing that PCa cells don't live on indefinitely like zombies, but rather undergo the process called
apoptosis, the normal, programmed cell death that the majority of healthy cells in organs undergo. We don't want simply toxic substances, which would kill off healthy, as well as malignant, cells. Rather the goal is to get PCa cells to go against their genetics and die a "natural" death.
Djin
Post Edited (DjinTonic) : 1/9/2020 10:45:08 AM (GMT-7)