PSA shocker !

Hello friends , as you can see my signatures PSA results after 5 yrs of up and downs , usually the ups were done at VA . the others were done at the same hospital . I had SBRT , cyberknife , 5 treatments .almost 6 yrs ago i recently seen my Uro.and he suggested a ultra-sensitive blood draw because of the ups and downs which I had last week . Well today his nurse called and told me my PSA was 3.07 . I about shat . My nadir lowest was .83 so double that would be 2.49 before you have to be concerned . Im concerned . his nurse mentioned that a another ultra sensitive blood draw in 4 months but i told her in 2 months . She also mentioned the Uro.said a MRI if needed after the next PSA .Am I in order for a PSMA or other imaging ? I have not called my Rad Onc yet but I will to get her opinion . Any thoughts on this would be appreciated . Thanks All ,

My RO has not bowed out but she has been monitoring my PSA from day 1 . I just go to the Uro every 6 months for wellness check . Last I talked to RO she said that with those low psa numbers scans would show nothing , like mets . I will talk to her soon . Thanks

I'd like to remind you of the "standard" advice all the more-experienced guys gave us before. . .

Whenever a single test is way out of line with the recent trend, re-test ASAP. This one could be a lab error. If so, you don't need the stress of having to worry about it for months until some doctor is willing to look at another number. I would push for an immediate re-test. After all, even from the 1.7, that is a big jump.

Also, did they consider antibiotics to rule out any prostate infection activity?

I do admit that your trend is concerning, though. I'd expect Dr. Hirsch to be more than willing to discuss and strategize with you.

311 - What Djin and Paxton said - retest asap, dont wait two months.

In my first year after prostatectomy, i had 3 tests 3 months apart, all resulted as <.02 . My fourth test was 3.8. I retested the same day i got the result, and got an undetectable. When i contacted Quest, they looked into it and said it was lab error, they retested the same blood sample multiple times and it always came back as <.02.

So get thee back to the lab for retest, before you start thinking about next steps. If you still get the same or similar result, then i would say yes, PSMA PET scan is probably in order.

Thanks Guys , I e-mailed Dr. Hirsch my RO and see what she says . I will ask her for a script for a regular PSA where all of them were taken at Silver Cross Hospital . I still dont understand the upsa . So what is my true PSA , the 1.7 that I took 7/13/21 or the 3.07 upsa that I took on 10/28 ?