This would certainly be a problem, if it is even that, for only a very small population, those people who, born males, transition themselves through artificial means into female-like bodies.
Which raises a number of gender issues. One being, if a person who does this still has a prostate, that is, it was not removed during the "regendering" process, and the rest of the person's body is now hormonally female, is there still risk of prostate issues for that person, including prostate cancer?
A first thought might be that, after all the effort taken to feminize such a person's body, a transgender female's risk of prostate cancer would be that of a normal woman: none.
However, the article below maintains that if a body, whatever its gender state, still has a prostate in it, the regular health issues associated with the gland will continue on.
From the article:
"Basically, if you have a prostate, you're at risk of developing prostate cancer."
"For transgender women who have had gender-affirming surgery or are on hormone therapy, the risk of prostate cancer seems to be very low. But if you have transgender women who haven’t been on hormones, then their prostate cancer risk is the same as cisgender men.” (cisgender= "denoting or relating to a person whose sense of personal identity and gender corresponds with their birth sex")
"The screening process is similar for transgender women. It’s not currently recommended that doctors regularly screen transgender women for prostate cancer."Obviously this is a pretty small subset of the people who develop prostate issues or prostate cancer.
The sort of thing that perhaps holds some interest for its uniqueness, but is otherwise a concern only for those who are involved with it.
But it's unusual to be sure, and a curious issue for some in the PCa world.
https://www.self.com/story/transgender-women-prostate-cancer-risk#:~:text=prostate%20cancer%20can%20and%20does%20happen%20to%20transgender,of%20her%20body%29%2c%2031%20years%20after%20she%20transitioned.