groundhogy said...
...Does they body have any function that will pick up these cells or debris and move them to the trash bin (lymph)?...
Men newly diagnoses are understandably concerned with cancer cells "escaping" from the prostate. However, it's not rare for circulating tumor cells (CTS) to occur. Fortunately, it is extremely difficult for these rogue prostate cells to gain the ability to establish themselves and grow in other organs or tissue as a metastasis--it can take years for this process to happen,
especially in those men whose cancer is genetically predisposed toward metastases.
You can have your biopsy tissue (or your post-RP tissue if your choose surgery) tested to see if you are low-, average- or high-risk for metastases within 5 years of the time the tissue was taken. The more popular tests, and those more likely to be covered by insurance, are Decipher, OncotypeDx, and Prolaris. (Depending on your risk category, your insurance may cover a genomic test test.)
The conventional wisdom had been that metastasis risk was proportional to one's Gleason score. Genomic-testing results have shown that met risk cuts across
all Gleason scores. For example, I had a G 9 (4+5) staging, but tested low risk; about
10% of confirmed G6 (3+3) men test high risk for mets (meaning not that G6 can itself metastasize, but that they are high risk for developing higher-grade lesions that can metastasize.) What
does change is that the
percentages of men in the low-, average-, and high- risk categories shifts toward high risk as the Gleason score increases, as you would expect.
Post Edited (DjinTonic) : 6/13/2022 1:48:49 PM (GMT-6)