Hi Princess -- it's definitely the Prednisone. I too had those terrible nightmares, the craziest dreams and lots of sweating. Also during the day I felt like my head was going to spin. I had a lot of good workout during my prednisone days though! Gave me lots of energy. Have you tried some herbal tea before you go to bed such as Camomile or Sleepytime? That might soothe things a bit.