Feel Jittery Buzzed Weird on 6-MP

I don't know what to think anymore. It's so hard to tell what medication is causing what symptoms or if it's all in my head.

I started taking 6-MP almost three months ago. Started at 50 mgs and just increased to 75 two weeks ago. I've been tapering off prednisone during this time and am down to 10 mgs. My UC has been fine during this time. One or two solid bm's a day and no bleeding.

However, I feel weird. I can't quite explain it. Yes, I'm tired (exhausted some days) but can't tell if it's the medication or the fact that I work full-time and have a toddler. At times I will get so jittery out of no-where, shaking and I have to eat something right away. I eat three good meals and snacks a day. I also feel slightly nauseated at times. I haven't thrown up, but just an uneasy stomach (this is unusual for me). Also, this is what has concerned me the most, is I have noticed a tightening in my chest a couple of times in the last two months. I've never really had heartburn, but it doesn't feel like a burning sensation, more like I really notice my chest area. I have a little hair loss too, is this from the 6-MP or prednisone?

So, I mentioned all these things to my GI doctor and asked if these are common symptoms with 6-MP and he said it's hard to say and to keep a diary of when I notice these things (which I've started). I've also asked if I would be better off taking it in the morning vs. night and he said it's personal preference. I just started taking it at night two weeks ago, not sure it makes a difference. He is closely monitoring my blood and wants to see how I do when I come completely off the prednisone this month.

To make a long story short, my question is are these things normal or is this in my head? If these are normal symptoms do they eventually go away? And if so when? I have another question about my Colazal, but think I'll start a separate thread. Thanks for your insight.

Thanks Kmach. I started taking the 6-mp at night two weeks ago. I think it helps a little bit. Like I said, I could just be tired because of trying to do too much. I've very anxious to see how I do when I come off the prednisone completely this month. One thing that concerns me is th 9 Colazal a day. I swear when I take the full nine my stool is softer, but if I take just 3 or 6 a day, but stool is much firmer. When I mentioned it to my GI he said he wasn't sure why that was, but that I really needed to be sure to take the full 9. The reason being he said that research has shown that consistent taking the 5 ASA's medication helps prevent colon cancer. I'm sorry to hear that it hasn't helped you after 7 months of taking it.

Lightenup - Thanks for the suggestion. I didn't know that about prednisone raising one's blood sugar so maybe that is what is going on. I will see how I do once I completely get off of it this month and be sure to mention it to my GI. I appreciate the suggestion.