6MP-WHEN DO SEE CHANGES?

Hey 3time champ...it usually takes a little more then 3 months for the medicine to kick in, if it even doess.  I've been on 6mp since May (going on 6 months) on a variety of doses (see signature) and havent really seen much improvement.  I think the reason is that, I'm like you, 6 foot 3, 180 lbs (lost 30lbs since being dx) and only on 75mgs.  My GI mentioned that you should be on at least 2mg per kilo for 6mp to work and your prolly about 115 kilos if you weigh 230lbs.  The only issue is that I dont think its physically possible to be on the amount of mg's of 6mp for it to be actually working.  I felt near death on 100mgs....

Good luck, hopefully it kicks in for you!

     I've been on 6MP for seven years too.  Not sure if it even does anything.  The doctor had to take me off it twice.  First time was last year.  When I was admitted to the hospital my amylase and lipase levels were off the wall...really, really high.  The doctor thought the 6MP had affected my pancreas.  However, a week later, the levels returned to normal.  Three months later, still on prednisone, the doctor put me back on the 6MP with careful moderation of my pancreatic enzyme levels.  They have been within normal limits.  This past May I started to flare again after a seven month remission.  The doctor increased my 6MP to 100 mgm (I was on 50 all along).  My white count dropped to 1.6, so he stopped the 6MP once again for only three weeks, until my white count went up to 5.0.  Then he restarted it at 50 mgm again..oy.  I am still in a flare, not bad though.  I have been off the prednisone since the beginning of Sept and REFUSE to go back on it again.  I just hope and pray these rectal meds do the trick.