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6mp and fatigue?

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Ulcerative Colitis
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Posted 11/25/2009 2:44 AM (GMT 0)
I've been on 6mp for 15 weeks,i started on 50mg-went up to 75mg after one month-then 100mg,now 125mg.I'm getting fatigued all throughout the day since moving up to the 125mg.Anyone out there experience this?I'm 6-5,220lbs-thanks
Posted 11/25/2009 2:49 AM (GMT 0)
     I was very fatigued on the 6MP too...just felt yukky when the doc increased it to 100 mgm last summer.  Have your white count checked.  Mine dropped to 1.6!!!!  Doc took me off of it now and I started Remicade last Wed..  Fatigued on that too..lol.
Posted 11/25/2009 3:05 AM (GMT 0)
I have been on 6mp for years now... maybe 5 or 6 years. My doctor said that he's never heard of the medicine causing fatigue, but I'm convinced that it does. I actually reduced my dosage (from 100mg down to 50mg) after discussing it with the doctor this summer. I noticed less fatigue... but still nowhere near the energy of a normal person. I attribute much of the need for rest to me simply having Ulcerative Colitis. Sometimes when on the higher dose of 6mp it almost felt like I was slightly poisoned. It was just a weird uneasy feeling, not a dull feeling, but throughout my body. It went away after decreasing my dosage. Unfortunately, with a decreased dosage my disease is more evident. It's a battle! I've used the time at the lower dosage to implement a steady exercise routine into my life... which gives me a little more bounce when I do have energy. I am thinking of upping the 6mp again, but really hate to think of what it might be doing to my body.

If it matters, I'm 6' tall, and around 165lbs right now.

Good luck with everything.

Zach
Posted 11/25/2009 3:34 PM (GMT 0)
I just talked with my gastro and he said he see's fatigue in patients more from the Pred being decreased[my 6mp went to 125mg and the pred was cut to 7.5mg from 10mg on the same day].On the sheet we get from the pharmacy it says that a side effect of 6mp can be fatigue,so between 6mp and pred i should feel tired,if it is going to get me better i'll deal with it.HAPPY THANKSGIVING
Posted 11/25/2009 9:55 PM (GMT 0)
Try taking the 6mp at night before you go to bed. I found a big difference with the fatigue during the day...its not completly gone but definitly alittle better. And i know the prednisone taper does make you tired too. Im now down to 10mg and dropping to 5mg on saturday...can't wait!! Hope things improve for you.
Posted 11/27/2009 5:25 PM (GMT 0)
Lynn isn't going from 10mg to 5mg a little dangerous.Once you get to taking a lower dose you should taper slowly,that's what my gastro has always done with me.
Posted 11/29/2009 10:28 PM (GMT 0)
3timechamp....i have been dropping by 10mg for the past few weeks. and doing okay so far. I am on too many immunosupressents and they want to atleast get me off the prednisone since i have been on it for 6 months. I go to the gi on thursday so i will mention it to them. They are actually having me just stop next saturday after taking the 5mg for a week.
Posted 11/30/2009 12:34 AM (GMT 0)
When does the fatigue occur and for how long? Are you taking steriods too?
Posted 11/30/2009 12:51 AM (GMT 0)
Burli read my post from the 25th,i'm on pred.I take my meds in the morning and i get fatigued during the afternoon.
Posted 11/30/2009 3:03 AM (GMT 0)
6mp makes me tired. i didnt notice it on 50 mg but do on 100mg. my GI prescribed me this but because i live in an isolated area i cant always see him and sometimes have to see a general practitioner. when the 50mg was not working for me the gp had a look in his pocket reference guide and told me to take 250mg. what an arsehole. this dose made me so fatigued i could hardly get out of bed. i have a family to support so i got up and went to work (Labourer) everyday anyway. this was one of the hardest things i ever had to do. this went on for 5 weeks untill my gi came to townc and sorted it out. to cut a long story short, 6mp will definately make you feel bad if you take enough.
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