I take Asacol - 12 pills 4x day. I take them at 6, 11, 5 and 9. I find that in the morning, because it has been so long since I have taken a pill, I have cramping and pain. Within 20 minutes of taking my first daily dose, the pain and cramping goes away. I tried keeping the 9 pm pill until I visit the bathroom in the middle of the night but I don't always get up or even remember if I do.
I was interested in what times of the day everyone takes their pills and do you find you have to move up the times sometimes?