HealingWell
Search Close Search
☰

Elevated LFTS

Support Forums
>
Ulcerative Colitis
✚ New Topic ✚ Reply
❬ ❬ Previous Thread |Next Thread ❭ ❭
Posted 8/22/2010 4:53 PM (GMT 0)
Hello,

I have had UC for 14 years, diagnosed first at age 19. First it started out
to be left sided and after my last colonoscopy it turned out
to be pancoltitis. I have had flares off and on. Currently
I am on lialda and rowasa enemas. Recently I have had a high alkaline
phospatase level of 141, my GGT was normal. My doctors were saying that it
could be do to a number of things like recent pregnancy ( which I did have a baby
a few months ago, and also they said it could be because the colitis
is active at this point). My worry is that there is a strong association with cholangitis.
My question is have any of you had an elevated alkaline phosphatase with your UC and it turned out
to be due to the colitis being active. I am seriously worried that I could have this PSC and everybody is
brushing it off as maybe this or that.

Thank you for reading this

Natal
Posted 8/22/2010 6:43 PM (GMT 0)
Hi...yes, it could be due to your recent pregnancy and now flare as well as being on 5ASA meds.

You do need to me monitored. What are your other tests such as ALT and AST?

If you are worried about PSC....you should have an MRCP done. It's a liver/abdomen MRI.

DO NOT give in to an ERCP.

Your worries won't change a thing. You need to do the research and make sure you have the pertinent blood testing done...etc. plus an MRCP.

I have PSC, confirmed by an MRCP. My liver enzymes, especially the pertinent ones were high for many years, but I refused an ERCP because it can cause pancreatitis and possibly activate the PSC if it's in early stages. Some things are best to be left alone, especially since there's nothing that can be done to change it.

How are your other tests....?

Welcome to the forum.

quincy
Posted 8/22/2010 8:59 PM (GMT 0)
My doc suspected PSC when my LFTs went up for a period.  It was not.  I had an ultrasound but put off MRCP (and biopsy) to await more blood tests.  Six months later, the numbers were normal (though they do go up from time to time).

Another poster suspects Lialda is leading to his high LFTs.

Posted 8/22/2010 9:42 PM (GMT 0)
Biopsy...I wouldn't have one either..but it wasn't suggested.  The MRCP doesn't have one doing a biopsy at the same time.  It's usually done with an ultrasound.


q

Posted 8/22/2010 10:44 PM (GMT 0)
I would not worry about it. 150 is the upper end for many labs and pregnancy, inflammation, some anti-inflammatory drugs,plus many other meds..all raise ALP . GGTs are going to be high also if you have a serious problem but many times both numbers are high and there is no problem.

My LFT numbers were all over the place when I was in a flare and they went to normal after a few months. I had high ALP and GGT plus low albumin.

Talking to the doctor I got the impression that numbers are off the chart, or you have a combination of bad numbers plus symptoms before you worry.
Posted 8/22/2010 11:55 PM (GMT 0)
I was going for an ultrasound for a suspected aortic aneurysm that was coincidental to high LFTs.  My GP figured we'd kill two birds with one stone and wrote the ultrasound scrip for possible aa and possible enlarged liver.  No aa and no enlarged liver. 

(I keep telling myself that one of these days I'm going to stop listening to doctors.)

My GI wasn't satisfied with that, so he wanted an MRCP and a biopsy.  I agreed to the MRCP at first and refused the biopsy.  Then, I did some more research and decided to cancel the MRCP and wait for more blood tests. 

The LFTs went back to normal, so at least I saved myself some time and aggravation.

Posted 8/24/2010 1:40 AM (GMT 0)
Thank you for those who replied. I feel lucky to
have found this place.
I'm hoping that things will turn out okay.
I think that I will just wait and repeat my LFT's and
see what happens after that.

Natal
Posted 8/24/2010 7:15 AM (GMT 0)
and please, please consider to get a copy of the results! It'll be good for future reference and research on your own.

q
✚ New Topic ✚ Reply