I was initially on Asacol 400 mg 6 daily for 6 months. My GI felt we could do better and suggested Apriso 0.375 gm 4 capsules every morning. Less pills to take is GREAT. Overall, I feel that I'm doing pretty good. Every so often I "flare". I really feel the Metamucil has helped a lot and more often than not, I have "formed stools", my new normal. I last saw the GI in July when I had an endoscopy/colonoscopy. At the time he said everything looked fine. I have no appt scheduled at this time but plan on calling for a 6 month check. Rectal meds haven't been mentioned by the GI at this time. I guess I myself feel that I really don't need them? Thanks for responding.