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Bad abdomen ache when taking 6MP--after two months.

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Ulcerative Colitis
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Posted 9/26/2011 1:44 AM (GMT 0)
I began taking 50mg 6MP (generic) at the end of June, and didn't feel any side effects, and blood tests came back fine. However by the beginning of September I began having really bad upper abdomen aches about 6 hours after taking the 6MP, towards the middle and left side. I always took the 6MP at night before bed to minimize nausea or upset stomach, but this is more of a punched in the stomach kind of harder pain.

I feared for my pancreas and absolutely had to stop taking it after a couple of days as the pain was too much to deal with. My GI has scheduled me to come in for blood work, but there is no way I can continue taking it if the pain is this bad. I am ready to start looking at LDN as my GI's by the book method has not helped me after nearly 3 years.

Anyone else had this sort of reaction to 6MP after taking it for over two months?
Posted 9/26/2011 4:21 AM (GMT 0)
If you are still in pain you really should go to the ER- you don't want to risk pancreatitis and you would need immediate treatment.
Good lukc and hope you feel better
Posted 9/26/2011 12:10 PM (GMT 0)
I'm sorry that you're having such pain. I never had that when I started on 6mp luckily. However, when I began Allopurinol with the 6mp I did. It hurt pretty bad so I can relate (I found out that I was allergic to Allopurinol). My pain was also in the middle.
Posted 9/26/2011 4:56 PM (GMT 0)
I stopped 6mp due to bad symptoms while on it (lots of fatigue, dizziness) with no positive improvement to show for it's use but my UC rarely has pain and didn't on 6mp. I would have stopped it sooner if I'd had pain.

The scary part (for me) about quitting 6mp is that my next med was going to be Remicade and I didn't want to start that. My GI put me on Balsalazide (generic Colazal) when I told her I quit 6mp and that also gave me no improvement (previously took large doses of Asacol for years with no improvement).

So the question for you is: what's next. New multi-antibiotic treatment?
Are you using retention enemas like Rowasa?
Posted 9/26/2011 5:15 PM (GMT 0)
I also has terrible abdomen pain from 6mp
after 3 month my blood test was bad and my GI told me I cant take 6mp
It reduce my white cells to much
Posted 9/26/2011 5:21 PM (GMT 0)
Either way, the pain was too much to deal with, it was worse than my colitis symptoms. I have been off it about two weeks and free of that pain. But still flaring. I think I got a stomach bug because it hit suddenly this weekend with a lot of D and fatigue.

In the past I discovered that I seemed sensitive to 5ASA medicines. I tried Canasa and Lialda for a while and it seemed to help, but eventually led to increased bleeding and D. My GI didn't want to accept this and put me on Apriso, which had the same reaction. I wouldnt mind trying the Rowasa again, but I fear I may not be able to handle it. Next step looks like LDN, since I've heard about so much success with that, I think its worth trying before stepping on the biologic meds.
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