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I think my pills make me worse.

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Ulcerative Colitis
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Posted 4/28/2012 6:56 PM (GMT 0)
I recently started adjusting the number of Asacol pills I take. When I take the recommended dosage, I feel really horrible. I get very very constipated and have stomach cramps after eating. When I stopped taking my pills, I started feeling better immediately. I really think my pills make me worse. Has anyone else experienced this?
Posted 4/28/2012 8:56 PM (GMT 0)
How long have you been on the Asacol? What are your UC symptoms currently? People that seem to have trouble with mesalamines usually get an increase in symptoms but I haven't heard about it making them constipated. I am in remission and I do tend to get constipated. I think thats part of having IBS as well.
Posted 4/28/2012 9:24 PM (GMT 0)
When I started Asacol, I had severe stomach cramping. My dr didn't believe it was from the Asacol so I agreed to try it one more time. This time I ended up in the ER with pancreatitis. The dr. believed me then. How long have you been on the Asacol?
Posted 4/28/2012 9:29 PM (GMT 0)
I have been on asacol or apriso for the last 5 years, but recently it has been making me feel worse instead of better. I feel imflamed a lot of the time, but I don't have diarrhea. I was in full remission when I started, but I've been feeling worse the last couple years. Stress and certain foods make it worse. My doctor suggested increasing my dosage, but after a couple weeks, I feel much much worse than before. Unfortunately, I can't see him again until June.
Posted 4/28/2012 11:23 PM (GMT 0)
Sounds like your not tolerating it anymore. Where is your UC located? Rectal meds may be of some help. Avoid food that you know may bother you if your feeling inflamed...in fact eating a bland diet for awhile may help. As for stress, I know the feeling well on that...the first sign of stress and my gut goes nuts. Will your GI call in something different for you to try?
Posted 4/29/2012 4:40 PM (GMT 0)
I agree with sherbear, it may be an intolerance. Have you ever tried Colazal? Some people tolerate it better than Asacol. I did worse on Colazal but it may be an option for you. You also may just require more than Asacol to stay in remission. Is that possible? I hope that's not the case. Have you tried any rectal meds? Maybe you're inflammaed in an area oral Asacol doesn't reach?
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