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Amino Acids for Mucosal Healing

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Ulcerative Colitis
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Posted 6/16/2012 12:21 PM (GMT 0)
According to an article referrenced in another thread, the amino acids threonine, serine, cysteine and proline are required to promote mucosal healing.
Has anyone found a supplement that contains these ingredients?

Posted by kickboxer:
http://jn.nutrition.org/content/136/6/1558.full.pdf+html
Posted 6/16/2012 1:15 PM (GMT 0)
I may have found a supplement on pure formulas: www.pureformulas.com/amino-complex-90-capsules-by-seroyal.html that has all four, in capsule form.
Posted 6/16/2012 1:41 PM (GMT 0)
Thanks for looking, stereo-

I also found Nutricology Free Aminos on Vitacost and Amazon for $18.61/100.
Contains 3 of the aminos plus 5-HTP which is supposed to help with sleep.
I'm trying to avoid buying one supp at a time....now have more bottles than I ever wanted. Also try to group purchases to avoid shipping fees. Call me frugal :-)

BTW- I noticed that Vitacost is offering $10 off for new customers. I took advantage of that a while ago.

Have a great day!
Posted 6/16/2012 2:19 PM (GMT 0)
This stuff seems to be a very expensive hydrolyzed whey.

Old Mike

http://www.pureformulas.com/amino-complex-90-capsules-by-seroyal.html

Post Edited (Old Mike) : 6/16/2012 9:33:55 AM (GMT-6)

Posted 6/17/2012 2:31 PM (GMT 0)
More info on amino acids:

http://www.livestrong.com/article/425336-9-essential-amino-acids-in-soybeans/

I saw a soy-based liquid amino acid product by "Bragg" that is very reasonably priced on Vitacost. Bragg also has a nice website and offers free samples of some products. I've gotten them in the past.

Maca and Whey powder used in morning shakes contain amino acids (including threonine) as well.

I have to admit I'm reluctant to purchase individual amino products when there seem to be many sources, including foods, that provide a variety.

Any comments?
Posted 6/17/2012 3:42 PM (GMT 0)
I cant remember, did you find L-Threonine powder helpful?
Posted 6/17/2012 3:44 PM (GMT 0)
It's always something - I too thought why not just get all my amino acids from my diet, but a lot of the articles i've read seem to state that essentially if you are in a flare the best thing is to supplement because you simply cannot ingest enough through diet to satisfy you bodies needs while it is trying to heal. Especially L-threonine and other amino acids that your body does not produce on its own.
Posted 6/17/2012 7:24 PM (GMT 0)
stereo-
I have not purchased L-Threonine as a separate supplement.
I was exploring the possibility of buying an amino acid "combo" product when a comment by Old Mike (above) made me take a look at the products I am already using...whey powder and maca for morning shakes.

kickboxer-
I agree that when you're in a flare, it's probably wise to take a supplement but I seem to have the "flare" issue under control (knock on wood).

Don't want to get carried away with buying......I pay out-of-pocket for LDN, probiotics and other supplements.

Currently looking at kefir to get max probiotics at least expense.
:-)
Posted 6/18/2012 3:31 AM (GMT 0)
I went on Mercola's website to see if I could find the label that listed which proteins the whey protein powder contains and I found this information about protein isolates. It would be interesting to hear what the scientists who performed the experiment think about what Mercola says about isolates. Just more to consider (and all the more evidence to use supplementation with caution.


Whey protein concentrate, NOT protein isolates

Protein isolates are proteins stripped away from their nutritional cofactors. There are three problems with that...

All isolates are exposed to acid processing.

Your body cannot assimilate proteins in isolated form.

Due to over-processing, isolates are deficient in key amino acids and nutritional cofactors.
Posted 6/18/2012 6:57 AM (GMT 0)
I took 3 5-htp pills tonight. I take them frequently.

Just be aware my bottle says to not take if you have ULCERATIVE COLITIS.
Posted 6/18/2012 9:33 AM (GMT 0)
IAS,

One of the many reasons I take at least 2 whey protein shakes a day is to ensure I am getting adequate quantities of all amino acids in my diet (IMO you can't rely on just our foods to get them), and of course, I have found it to help with my UC.

Adding the extra L-Glutamine and extra L-Threonine (separately) has only added to the goals of long term mucosal lining repair as evidenced by the perfectly formed BS (as in pre-UC diagnosis).

IMO, it's been a win-win. Although L-Glutamine is a little more expensive than L-Threonine, I have found the L-Threonine to have given me much more bang for my buck, because that in itself is what caused the perfectly formed BMs on a consistent basis.

As a result, I have been able to cut back on the L-Glutamine from 15g to 5g daily. I don't think I will cut back entirely on the L-Glutamine as it is a precursor to Glutathione production, which is important in auto-immune diseases.

I would offer to send you enough for 4-5 days' worth of trial of the L-Threonine of the amino acid powder, but I'm afraid the USPS might mis-construe it "anthrax like" and send the FBI to my house, lol. :-)

Posted 6/19/2012 12:56 AM (GMT 0)
InSoFla-
Thanks for the offer......:-) but I think you may be missing my point.

Aside from the expense, I am sick of taking a bunch of stuff every day and don't want to add to it if I'm already getting the nutrients I need or can find a product that combines several.

I take l-glutamine in juice first thing in the morning on an empty stomach with my Benebiotics. Also mix up shakes containing whey, maca, almond milk and fruit.
At some point during the day, I try to remember to take Osteo Biflex, calcium, D3, a multivitamin with iron, and fish oil not to mention 3 caps of colazal twice daily. Have to space them out because taking all at once results in stomach upset.
(Some days when I'm away from home, I skip everything but the colazal.)
Then there's slippery elm with probiotics at night before applying LDN around 10pm.

I hate having to add yet another product if I can avoid it.
Also, I think I can get a good many nutrients from food and would prefer to do so.
Posted 6/19/2012 1:10 AM (GMT 0)
Itsalwayssomething, I understand where your coming from. Having to add more supplements and not finding results is tiring. And I've taken whey protein since day one, but never seen results that I am currently noticing. I have to back InSoFla, that after she presented her findings on L-Threonine, I ordered an inexpensive, small container, and within one week I've experienced amazing results! Perfectly formed bowels, no nausea, aches, etc. I know it may not help everyone, but if this is the amino acid that I need to maintain a balance, maybe there will be others who can benefit as well. :)
Posted 6/19/2012 1:19 AM (GMT 0)
stereo-
I'm not against taking L-threonine. I'm already getting some in the whey and maca that I use.
I'm just wondering if it would be wiser to take a product like Bragg soy-based liquid aminos that contains a whole "laundry list" of aminos instead of adding one at a time.

From the Bragg website:
Bragg Liquid Aminos is a Certified NON-GMO liquid protein concentrate, derived from healthy soybeans, that contains the following Essential and Non-essential Amino Acids in naturally occurring amounts:

16 Amino Acids

Alanine
Arginine
Aspartic Acid
Glutamic Acid
Glycine
Histidine
Isoleucine
Leucine
Methionine
Phenylalanine
Proline
Serine
Threonine
Tyrosine
Valine
Lysine
Posted 6/19/2012 4:30 AM (GMT 0)
I consume a variety of amino acids every day for years. All natural whey protein, Pure Green Protein and now enteric coated protein blend. The last two have been the most beneficial. So I am quite sure I get enough of every essential amino acid in a full spectrum blend.

What works best for me is salmon and filet mignon plus pure green protein and the enteric coated dymatize.

However I always keep an open mind and took my first 2 grams of l-threonine just before bed instead of another dymatize shake per InSoFlo. That and the 4 chicken sandwhiches I ate today after egg breakfast and I am sure I consumed plenty of each essential amino acid.
Posted 6/19/2012 11:27 PM (GMT 0)
IAS,

I understand your being fed up with taking "all the stuff" and its associated cost as well.

It certainly wouldn't hurt to try an "all inclusive amino acid product", however IMO, I don't think it will accomplish what the additional L-Threonine amino acid powder can bring to the table.

I say this based on several things:

1) The actual content of bio-available L-Threonine within certain foods is hard to determine and calculate.

2) I found a huge difference in results when I tried freshly steamed lobster (from live tank) vs. frozen lobster - and that's due to live tank ones having a huge amount of bio-available threonine vs. frozen ones having depleted levels.

3) Since so much of our foods are processed, etc... and don't come directly from the farm to the table, etc... if we extrapolate the live tank vs. frozen lobsters to other foods, how do we know it wouldn't yield similar results?

4) Based on the results and the scarce studies showing threonine promoting and involved in mucosal lining repair, could it be that IBDers are missing this important Threonine or perhaps are deficient, and thereby need more of it?

5) Lastly, I am consuming several whey protein shakes daily, which do contain the whole range all amino acids, and yet I had no such results. BUT once I added threonine, BINGO!

Ultimately, it's your decision, and I well understand your being sick and tired of taking supplements.

:-)

 

Posted 6/19/2012 11:34 PM (GMT 0)
aguywithuc,

took my first 2 grams of l-threonine just before bed

and what were your results?

Any changes in:

- perfect BM

- pain

- deep sleep

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