Curcumin?

cayanne pepper seems like it would irritate. I'd be careful with anything too spicy.

This is from the reources thread:

Curcumin Use in UC: Links to Research on Safety and Dosing

 

• NIH fact sheet: Turmeric (Curcuma longa Linn.) and Curcumin
  http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-turmeric.html
• Curcumin (comprehensive 'summary' of the research for the public)
  Micronutrient Research for Optimum Health
  Linus Pauling Institute, Oregon State University
  http://lpi.oregonstate.edu/infocenter/phytochemicals/curcumin/
• Curcumin Therapy in Inflammatory Bowel Disease: A Pilot Study
  Digestive Diseases and Sciences, Vol. 50, No. 11 (Nov 2005), pp. 2191–93
  http://www.docstoc.com/docs/69229708/Curcumin-Therapy-in-Inflammatory-Bowel-Disease--A-Pilot-Study
  

I take Inflamma-blox by Ortho Molecular Products which contains turmeric root, bee pollen and skullcap, and it always helps my symptoms a lot. I take about 2500mg per day.

Thanks good to know although that product does contain rice!

The amounts used in the few clinical trials were 550mg to 1000mg. The addition of pepper is to promote the absorption. For UC, if the effect is topical, absorption may be less of an issue.

-----------------------------
Curcumin

Curcumin is a compound in turmeric (Curcuma longa) that has been reported to have anti-inflammatory activity. It has been found to induce the flow of bile, which helps break down fats. Additionally, it could reduce the secretion of acid from the stomach and protect against injuries such as inflammation along the stomach (gastritis) or intestinal walls and ulcers from certain medications, stress, or alcohol. In a preliminary trial, 5 of 5 people with chronic ulcerative proctitis had an improvement in their disease after supplementing with curcumin. Curcumin inhibits the activation of NF-κB. NF-κB promotes the synthesis of many antioxidant enzymes. Curcumin directly binds to thioredoxin reductase and irreversibly changes its activity from an antioxidant to a strong pro-oxidant.

The amount of curcumin used was 550 mg twice a day for 1 month, followed by 550 mg 3 times a day for 1 month.[39] Hanai and colleagues published the results of the first randomized, multicenter, double-blind, placebo-controlled trial from Japan to study curcumin's effect on UC maintenance.[40] All 97 patients who enrolled and 89 patients who completed the study took a standard dose of mesalamine or sulfasalazine and either 1 g of curcumin or placebo twice daily for 6 months and then were followed for another 6 months off study medications. The relapse rate at 6 months on therapy was greater for the placebo group than for those who took curcumin (P = 0.049). Thus, curcumin may confer some additional therapeutic advantages when used in combination with conventional anti-inflammatory medications in UC.

     Deja Vu...I tried all that stuff.  I do believe I kept the health food store in business for years..lol.  Nothing really helped....it didn't hurt, mind you....but didn't help keep me in remission either .

There may be more recent threads on Curcumin/Tumeric, but this one seems like a good one to tag on to.

Any updates from people that have been using it? How much are you taking? When do you take it? Any ongoing side-effects?

Thanks!
Eph

I take 2000mg/day (Doctor's best Curcumin with Bioperine). It helps me without any side effects.

Boy... I slacked on this one.
https://www.healingwell.com/community/default.aspx?f=38&m=2738611

I took it once last week and forgot...

I just took a 500mg Nature Made Turmeric... I'll take it everyday and post if I have any side effects.
From what I have read so far it is safe to take. I'll start on the ginger sometime later.... Don't want to introduce too many variables at the same time.

I am taking 2.4 g of Solgar tumeric for two weeks to try to reduce NF-kb. I'm supposed to reduce that to 800mg at the end of two weeks.

Undigested / in absorbed tumeric looks like gold flakes in the toilet :)