I have been on Imuran for 3 years at 150mg a day. I have had no problems but I went and had a colonoscopy two weeks ago. Now I have hair loss,stomach pain, join pain. My colonoscopy came back clean and I am still in pain when I have a BM. When I do have a BM I get hot sweats and chills, and pain so bad that I feel like I am going to pass out. I also have an incredible urge to push and I can't control that urge at all. Can anyone help? My doctors have no clue!