L-glutamine and depression

Your own experiment is the one that matters. I'd give it a bit of time then experiment again. If you dare, a third time, it's pretty good confirmation if you get the same result all three times. L-glut amine can be so helpful that I think it's really worth experimenting. I would also wonder about the fillers in the capsule...trying different brands might help

Right now I'm taking extended release, but when my GI first prescribed it he prescribed immediate release. Didn't make much difference on my symptoms and its easier to take just the one pill in the morning. Has anyone taken it and seen a difference?

What? L-Glutamine exacerbated your depression symptoms? I don't think I've ever come across something like this... are there any warnings or suggestions on the brand you have?

I dont see the L-Glut affecting depression, very odd. Try a lower dose to start?

Stereofidelic - no warnings on the box. But weird things affect me, like folic acid in any form, even eating broccoli, turns me into a very, very angry person, like I-want-to-punch-people-in-the-face kind of angry. At least I know I'm absorbing it lol. Never been the same since doing IVF - all those hormones and medrol changed my chemistry I guess. I'm normally a very quiet person, obsessed with being polite, seriously.

Zucchini - that's a nice side effect! Just started scd and am wishing l-glut did that for me too!

Madcat - it didn't necessarily make me more depressed, I should say, it made me angrier and I didn't want to do anything or talk to anyone, which I'm told is a manifestation of depression. Good stuff.

I took half a teaspoon of powder and mixed with water. I'll wait a week and try a smaller dosage.

If glutamine bothers you then please stop taking it. It is probably OK for short term digestive repair but the jury is still out about taking it every day:

articles.mercola.com/sites/articles/archive/2004/05/01/glutamine.aspx
The major use for high-dose glutamine would be to repair gastrointestinal injury. In such cases, I would recommend short-term use only...

Glutamine accumulation has also been found in Alzheimer’s disease, Huntington’s disease and high levels of brain glutamine have been associated with a worse prognosis in Lou Gehrig’s disease. Likewise, recent studies have shown that high brain glutamine levels increase brain levels of free radicals and impair the ability of brain mitochondria to produce energy. When the brain produces low energy, excitotoxins, such as glutamate, become even more toxic. It has been shown that the reason for glutamine toxicity under these conditions is because it is converted to the excitotoxin--glutamate...

Newer studies indicate that actually it is the glutamine that is causing the brain’s injury. Increasing glutamine in the diet would significantly aggravate this damage

docs are just so helpful, aren't they -

You are the first person to mention some type of side effect of L-Glutamine. I only would take 2g's of L-G at a time, and it would exhaust me. I would take it after a run or exercise, and it would immediately put me on the couch. So odd. Didn't do much for UC, however the recommended dose for UC is 15g, atleast 7x the label dosage.

Mindoverbutter, yes that's exactly how I felt. Couldn't move, just wanted to lay around (and hate people lol)! The day after, I didn't take it, I was a total spaz around the house - did loads and loads of laundry, dishes, organized my closet, played with my daughter and was in a great mood. Kind of manic, huh?

Were you on any anti-depressants at the time?