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double mesalamine enema??

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Ulcerative Colitis
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Posted 2/15/2013 4:27 PM (GMT 0)
has anyone ever been told (or tried on their own) to do 2 retention mesalamine enemas per day? I'm at max dose of oral and been doing nightly 4g enemas but bleeding and mucus are escalating... just wondering if anyone ever doubles the enemas with success? or would it be risky? got 4 days off so could afford the time to double up.
Posted 2/15/2013 5:08 PM (GMT 0)

i tried something similiar to that, i would do the rowasa at night and then an hour before i got up i would either do another rowasa or a hydrocort.  it did not help, in fact i found it was so much liquid and it wasnt absorbing well and i was all liquidy bowels that day.

that being said, ive gotten out of my other flares by doing a rowasa at night and then doing 2-3 canasa supps during the day.

however, ymmv, so its def worth a shot for you to try on your own

Posted 2/15/2013 5:11 PM (GMT 0)
If I expel an entire enema shortly after taking it, then I'll wait a few hours and try again with a new one. It's hard to tell if you are empty before taking an enema sometimes.

I did try taking two enemas a day (once at lunchtime and once at bedtime), for several days when this flare was first starting. Although, I found out it was too little too late though as it didn't help and I ended up needing the much stronger pred. From what I hear it is pretty hard to overdose on meslamine -- it is just an anti-inflammatory medication. I was taking 5 grams orally a day, and then the two 4g enemas. I had no really adverse effects that I could tell. I did have night sweats a little bit both nights, which could have been from the two enemas. When the GI scoped me early in the flare their was a lot of inflammation and it extended beyond the 50cm he could see with the scope, so I think the enemas just couldn't reach far enough for me...

Of course you can check with your GI before doing it...
Posted 2/15/2013 8:06 PM (GMT 0)
You can consider to ask the doc to prescribe you a steroid foam enema to use during the day.

While bleeding and mucus is escalating....how often are you having bms? and what's the stool consistency?

Are you using any probiotics and fibre supplements?

q
Posted 2/15/2013 10:32 PM (GMT 0)
had been doing really well for about 6 weeks, but about 2 weeks ago started seeing blood, then the mucus. went back to nightly at that point (was every 3rd night prior) Urgency and frequency are increasing but still manageable. going between 2-4 times per day. sometimes mucus clumps but when stool it is still formed. My GI is not a fan of enema's - thought of asking for cortisone enema. wish I could just figure it out on my own and not contact office. Guess i procrastinated the day away so can't call til Tuesday now anyway (long weekend in Ont.)

I am doing probiotics - no to fibre.

I don't want to wait til it's out of hand to call the GI but i also don't want to call if I can get things to settle again. Very frustrated as I thought I was pulling out of that last flare... Grrrr
Posted 2/15/2013 10:39 PM (GMT 0)
I've tried to do 2 enemas a day when I was very ill, but like iPoop said, often I would end up expelling one of them so I probably didn't get too much benefit. Usually i would use a 4g enema before bed and a suppository or foam in the AM. I used to call my GI every time something happened. Now that I am on 6mp, I have small blips that usually don't progress - i've learned not to bug her unless I am sure I am going to get worse. I think things went downhill a lot faster for me before I was on 6mp.
Posted 2/16/2013 2:37 AM (GMT 0)
My son did a half enema in the morning (10:00 a.m.) and an entire enema (4 g) in the evening before bed. I think the enemas helped him get off the prednisone he was on without relapsing. He has been doing the "double" enemas for 4 months and we are in the process of going down two just the 4 g evening enema. We have always just used the mesalamine enemas and he has never had a problem retaining them.
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