Making own nootropic energy drink to recreate incredible high dose prednisone brain 'hypomania'

They have me on a fast down taper in case I need the cath lab ICU surgery for hand. I wont. But I will miss this last ride of electric thoughts, creative solutions and working without sleep for weeks.

The Hypomanic Edge: The Link Between (A Little) Craziness and (A Lot of) Success in America

Going to continue making my own nootropic energy drink that has low caffeine, even the no creatine no arginine formulas dump 200mg caffeine in there which I really dont need and just makes my colon purge.

I want to stimulate my brain the way high dose prednisone ( hypomania ) does but without stimulting Gi.

Taurine
Huperzine
Alpha-GPC
Brain-Octane
Vinpocetene
Arginine Ethyl Ester
30 mg caffeine anydrous
1,3 dm ( not until clear of problem as this is vasoconstrictor )

Hypomania
Individuals in a hypomanic state have a decreased need for sleep, are extremely outgoing and competitive, and have a great deal of energy. However, unlike with full mania, those with hypomanic symptoms are often fully functioning. A number of high profile sources have cited that individuals suffering from hypomania are actually more productive, risk accepting, and goal oriented than usual. Examples of work that cite this idea include books such as The Hypomanic Edge by John D. Gartner

Many individuals who experience hypomania become extremely goal-oriented, sometimes to an almost obsessive degree. However, unlike mania, individuals in a hypomanic state are often able to keep these goals rational and concise, and can plan around them accordingly. It is for this reason that John Gartner asserts that many leaders throughout history have experienced some sort of mental condition that accurately reflects the characteristic of the hypomanic episode.

The Brain Octane has a lot of the stuff you already are adding such as caffeine and Alpha-GPC. Go easy on the DMAA as well. If that stack is similar to pred then I'd like to try pred :).

Thanks for the replies I love this subject. I have done my best most important work through all of this and from what I read depression for 4 weeks lies ahead as we remove pred. The sluggish unimaginative life is not appealing to me. If I can live this way ( with more rest ) and have no bad habits other than being in my optitmal state the happiness of life is off the chart. Problems are an endless stream. I am amazed how I organize a set of facts, get stumped, got to can or fetch a cup of water and the 'answer' slips into my brain as if on its own. Last time I tapered down I would lose track of what I was talking about mid-sentence. How on earth do you have the sustained continuity of thought to solve the hardest most challenging ( and most engaging and most fun ) problems that have stumped people around you for a long time ?

I think the blood thinners are diluting the pred effect so I am scrambling while the lights are bright to prepare for a soft landing.

Anemia no doubt contributes here and 4 days of iron infusion was apparently not the total answer, adding B-12 with folate sub lingual shots.

As for the diet question yes I believe I need more plants not fruit in my diet, every hospital meal was involving that and every doctor thought I was centered and hypomania. Yes 2 of the doctors were absolutely beautiful but I did not try to 'hit' on them as the definition of hypomania says the downside risk is spending ( I did ) and spontaneous sex - not at all I am 49 years old and a short term whoopie is not needed to stroke my ego, create awkwardness etc. The rest of hypomania seems positive to me, while mania sounds like you lose touch with reality get delusions of grandeur and become a jerk.

One doctor noted I had hypomania but I softly asked her if slowing my speech would help her cope with me and a big smile spread across her face and her medical notes said despite it I was 'pleasant' and I did enjoy that external validation that it does not make me an egomaniac jerk.

Have you considered smoking mostly a sativa based pot? It would be safer.. treat your uc and alot more fun. ;)

No Racetams in there? I used Piracetam for a while with good results. Probably better to wash the pills down with your drink though than to put power in there, the powder tastes nasty. Aniracetam is way more palatable though.

stereofidelic89 said...
aguywithuc, just wanted to suggest looking into some licorice root (glycerhizinated form) to help your adrenals encourage cortisol production as you taper the pred, so you don't get fatigue.

Good luck with the energy drink!

Yes that is part of my regime and more directly 2.5 and 1.25 pred pills for a really smooth long landing.

Tyrosine, Phenylalanine, l-DOPA are all similar. The Octane contains Acetyl-L-Tyrosine already but in low amount. Try 500mg of Tyrosine by itself to get an idea of that effect. Some interesting studies on Tyr on Pubmed. Have you looked at mild MAO competitors like Hordenine?

MAO messing with while on prescription meds? Eeek

Hypomania ia always an alluring state but when you have a gut whacked out on meds and unable to manage its own maintenance of things like seratonin.. yadda yadda.. you risk making yourself bipolar or excaberating an undxed bipolar issues when you start messing with these chemicals. especially pushing adrenal crisis while tapering off pred.

Guywithuc.. you are having a crapty week.. Sleep more, hypomania less?

PathogenKiller said...
MAO messing with while on prescription meds? Eeek

Hypomania ia always an alluring state but when you have a gut whacked out on meds and unable to manage its own maintenance of things like seratonin.. yadda yadda.. you risk making yourself bipolar or excaberating an undxed bipolar issues when you start messing with these chemicals. especially pushing adrenal crisis while tapering off pred.

Guywithuc.. you are having a crapty week.. Sleep more, hypomania less?

Well actually I got so much done is amazing, in fact I did it all easily and am looking ahead, lining up 1 year final warranty fix list on new custom home next month and of course April 15th taxes then I will enjoy the lasting benefits of all the great work I have been doing. Requested weeks off when kids get out in spring. Last night I was up until 4:00 am and wrote a command prompt to database hierarchical scripting invocation system that relieves my left hand but allows me and teamate to work swiftly to diagnose performance problems and extend it infinitely and ongoing.

The pred is going to be slashed here real soon ( yikes ) so fitting in a couple final home runs.

I am also preparing for the 4 weeks of depression that is expected when I am on nothing but my adrenals and licorice. I told my cooworkers I will be a moron for about one month.

But knowing life can be like this without pred destroying my body ? Yeah I want that lots of that.

sean88 said...
Tyrosine, Phenylalanine, l-DOPA are all similar. The Octane contains Acetyl-L-Tyrosine already but in low amount. Try 500mg of Tyrosine by itself to get an idea of that effect. Some interesting studies on Tyr on Pubmed. Have you looked at mild MAO competitors like Hordenine?

Phenethylamine, similar to amphetamine in its action, releases norepinephrine and dopamine. When taken orally, though, it is rapidly metabolized.

Abnormally low concentrations of endogenous phenethylamine are found in those suffering from attention-deficit hyperactivity disorder (ADHD) whereas abnormally high concentrations have been discovered to have a strong, positive correlation with the incidence of schizophrenia

Conclusion : good stuff but has a sweet spot, short duration and risk of schizo

Substituted phenethylamines
Some are psychoactive drugs, including stimulants, psychedelics, and entactogens, which exert their effects primarily through modulation of the monoamine neurotransmitter systems. Others, such as dopamine and epinephrine are neurotransmitters. The substituted phenethylamines include the substituted amphetamines, the substituted methylenedioxyphenethylamines and a large group of alkaloids derived from phenethylamines. This includes tetrahydroisoquinolines, benzylisoquinolines, protoberberines, aporphines, morphinans, protopines and narcotine.

Question : What is the point ? Thought they would say it lasts longer...because 'Phenylethylamine's half-life is 5 to 10 minutes'

Hordenine is widely sold as an ingredient of nutritional supplements, with the claims that it is a stimulant of the central nervous system, and has the ability to promote weight loss by enhancing metabolism. In experimental animals, given sufficiently large doses parenterally (i.e. by injection), hordenine does produce an increase in blood pressure, as well as other disturbances of the cardio-vascular, respiratory and nervous systems. These effects are generally not reproduced by oral administration of the drug in test animals, and there are virtually no scientific reports of the effects of hordenine in human beings.

Conclusion : Sounds like it has unwanted effects on cardio except for appetite suppressent no mention of nootropic characteristics.

Still digging...

Honestly I thought pred worked by converting lots of my muscle mass to glycogen as pure fuel for the brain. I read otherwise this morning. I think it involved glutamate.

Post Edited (aguywithuc) : 2/24/2013 6:42:18 PM (GMT-7)

Yeah, as PK said go really carefully with any of this stuff. The hordenine is not an inhibitor but more of a competitor to other MAO substrates. I can only give you my own experiences with it which were mild but good in the productivity category. For Tyr, the stuff I bought came in 500mg caps and I wouldn't take any more than that. Phenylethylamine(PEA) is different than the Phenylalanine that I mentioned. Even though PEA is supposedly metabolized quickly by MAO if you take enough you get an effect. Sulbutiamine is another. Takes like hell though.