Prednisone and Mezavant (and Metabolism)

Currently in a difficult flare... I've been on Mezavant 1.2g (x4) since diagnosis last summer and it held it at bay for a good six months. I've since flared and am having a hard time getting it under control. Last Friday (March 29), I began taking 40mg Prednisone in the AM along side my Mezavant.

Has anyone had any experience with these two drugs combined? Have you had more success spacing them out... say 40mg Prednisone in the AM with breakfast, and then Mezavant in the afternoon w/ lunch? I've been taking them all at once w/ breakfast every morning (as well as a Salmon & Fish Oil w/ Omega supplement) and have experienced little to no difference in symptoms.

Also, I've always had a pretty high metabolism. Pretty skinny dude. Does one's metabolism affect your reaction to the Prednisone. If this is indeed the case, is there a more opportune moment to take it during the day when your system may not process through the drug completely so quickly?

Any experience would be appreciated, not looking for definite answers by any means!

Interesting. Perhaps some blood tests are in order.

Thanks.

definately get bloodwork done. 

Mezavant also caused extremely itchy skin for me.  Several trips to the doc and they all said maybe dry skin once I switched the itchiness went away.   I researched things I found out that itchy skin was a symptom of elevated liver enzymes.

Do you take probiotics daily? adds good bacteria to the colon that is lost with all the bowel movements

Do you take a fibre supplement like metamucil nightly? it helps to bulk stools

How about vit D liquid? boost the immune system, many of us deficient and dont know it

I find all three to be extremely beneficial to the improvement of my  UC.

metamucil absorbs the water in the colon, it bulks the stool and makes it easier to pass so that you are not straining causing hemmeroids and even fissures.

It also cleans the walls of the colon.

It is a good fibre supplement to take but not the sugar free one.

Many of us here take metamucil fibre.  I take it every night before bed.

Probiotics depending on the brand add good bacteria, help with diahrea, firm stools, and improve overall health.

  Bio-k plus is a great probiotic its found in the refridgerator of the health food store and some grocers now carry it.  It has helped me out of the worst of my flares years ago but I still take it daily.  You need the good bacteria in the colon otherwise the bad take over and cause problems. I find it best to take on an empty stomach.

I see you are taking fish oils they are great but for some they cause loose stools.

yes take the one with sugar.