Some interesting info I have found in past few days

For last 14 days I'm in pretty bad flare up and I have finally decided to do something about it last week. I have spend few days just by reading various studies, bachelor works about probiotics, stories of other people with UC and found lot of interesting stuff I did not know before and what is most important, after implementing it I really feel better. My flare up is not gone, but I'm really better. Here are some of the most interesting things I found (sry to all of you who knew this stuff before, but maybe someone did not).

1. You need to slow down your bowel before taking probiotics so they have chance to colonize your colon.

2. Probiotics needs their "food" for proper function (mostly fiber inulin). According to one study just 5g of inulin daily can raise number of bifidus bacteria in your colon five times!

3. Psyllium is fiber, but so gentle that it is actually good for people with UC, it becomes something like gel in your colon, makes stool more formed, but still very moist, so it is good both agianst diarrhea and constipation.

So according to these first three points it should be much more efficient to use Psyllium+Probiotics+Inulin together than just probiotics.

4. probiotics are not only important because they replace bad bacteria, but also because they create butyrate in colon from fiber (inulin for example). Butyrate gives energy to colon, helps it to heal.

5. Saccharomices boulardii yeast - 68% of patiences in one study with mild to moderate UC achieved remission using just 750mg of yeast Saccharomices boulardii daily and mesalazynes. This good yeast kills bad yeasts and has many other positive effects on colon. Find more info about it.

6. People with UC in long term remission have higher levels of Prostaglandin D2. Taking vitamin B3 should rise levels of it and surprisingly i have found story of guy who says B3 helped him a lot with his UC. ( link in sources)

7. Leaky gut syndrome is something what every patient with UC should know about.

8. High Quality EPA (Omega 3) lowers inflammation of colon


So with this info I have decided to try few new things and contiue with some I already knew (EPA). I bought lepicol plus (psyllium+enzymes+bacteria+inulin). Enterol (Saccharomices boulardii) B vitamins complex (B3) and Zync.
After few days almost without food (just spinach,chicken breasts and broth to kill yeasts and bad baceria) I started to eat again after die off. i eat for three days now again. I had quite formed stool yesterday and even i feel inflammation is still there and I feel it is moving inside of me I have not visited toilet for 24 hours now. Im pretty sure its because of psyllium and after so many years it is really great to finally find something natural what can slow me down during flare up so probiotics and mesalazyne has chance to work.
I know that for you veterans this post is not very informative, but these are things I did not know a week ago and I thought that I know so much about UC. Especialy about fiber! All those years i have UC I thought that fiber is bad for me, because my colon is damaged and fiber is somehow scratching it and making it even more inflamed. Oh how surprised i was when I have found this info that the right fiber is not only not bad for my colon, but because of right bacterias creates butyrate of it is even vital for colon health! The leaky gut syndrome is also something I had no idea exists.
Ok that is all, hope at least someone will find this info useful.

here are sources:
http://www.lepicol.com/userfiles/file/natural-nutrients.pdf
http://health.groups.yahoo.com/group/isribd/message/11 - B3 vitamin story
http://www.imperfectlynatural.com/articles-1/probiotics-for-candida-overgrowth
http://wholehealthsource.blogspot.cz/2009/12/butyric-acid-ancient-controller-of.html
http://scdlifestyle.com/2010/03/the-scd-diet-and-leaky-gut-syndrome/

I used much more sources, but did not save them all.. just use google and you will find ton of info and many interesting studies on animals and humans on every topic.

Pathogenkiller.. you use lot of words I have no idea what they mean :)) but I will find more info about it. I start to think that if I will ever win against UC it will be because of understanding it and understanding how colon, food and generally whole body works more deeply. Thanks to God we live in time where we can find information on internet and share it. I believe vast majority of us can overcome this illness, you just need to the work and find what works for you.

PathogenKiller: If I have a documented MTHFR677 mutation (heterozygous) what B vits should I start with? Or, where can I find the info? TY

Geeker, depends on what else is going on.. But in general.. You want to avoid folic acid.. So avoid anything with fortification as well as direct supplementation. Also l-methyltetrahydrofolate and b-12 . Same info as above.. Make sure to take b12 with or before l-mthf so no methyl trapping occurs, the first couple weeks you may experience a slight increase in symptoms as your detox pathways open. You can also look at Trimethylglycine. At some point when you get a good dose figured out and your body starts working efficiently you will need to titrate down, cycle or skip days. Do you have any recent homocysteine levels? How did you find out about your polymorphism?

Great post, Funkyshank. I have already implemented many of the things you mentioned from members on this board with great results. I will check out the links.

Best...

Good thread.

PK some interesting points on those B Vitamins taht i had no idea about.

So 5l MTHF is teh one rather than Floic acid to ensure best absorption?

And hydroxocobalamin as the B12 to use if you have mercury issues? Which I probably do.
As I understand it that form of B12 can only be administered via injection. Is that right?

On your probiotics points, I use Florastor as the supplement that satisfies point 5 of your original post. When I first started taking it, I was taking 2 per day, and it slowed down my diarrhea markedly. I take one per day now, along with (see my sig) RenewLife 80 billion.

I've been a fan of psyllium -- both the husks and the seed powder (i.e., soluble and insoluble) -- for ages. I had a cat for many years with whom I had a peculiar connection -- we led these bizarrely parallel lives. So it was no surprise when I needed to start putting psyllium husks in his food to regulate his bowels. He never had abdominal pain or constipation again!