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Rectal meds?
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Ulcerative Colitis
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AnnaG
Regular Member
Joined : Apr 2008
Posts : 191
Posted 10/12/2013 7:34 PM (GMT 0)
I'm 2 +weeks into a horrible flare up I've been doing pred rentention enemas for one week,the first 2 days It was so inflamed I could'nt hold hardly any in.Last night I got all but the last cm in and it stayed in all night it has made a big difference I did,nt get hardly any bleeding all today and it's just started a again this evening.
I do tend to bleed a lot when I'm in a flare and it's v.painful passing clots etc.
What I would like is to try and ride out this flare without starting on oral pred,how long would you carry on with these just these enemas,I'm a bit worried because I've already lost quite a bit of blood and I'm starting to feel quite tired I can't let the bleeding go on to long unchecked as I'm quite skinny and get anemic and real sick looking quite quick.
I am also starting on psylium seed which I believe has helped in the past to keep pushing everything through.
TroubledTurds
Veteran Member
Joined : Jan 2004
Posts : 8717
Posted 10/12/2013 7:42 PM (GMT 0)
if things are moving in the right direction, keep doing what you are doing -
pred isn't the end of the world, but you're wise to hold off if the enemas are able to do the job -
momto2boys
Veteran Member
Joined : Jun 2013
Posts : 2651
Posted 10/12/2013 10:52 PM (GMT 0)
Three weeks is fine without a tapering schedule, beyond that you will want to wean off of them, every other day for two weeks, then every three days for two weeks.
quincy
Elite Member
Joined : May 2003
Posts : 33769
Posted 10/13/2013 2:33 AM (GMT 0)
Firstly...make sure you have refills from the doctor.
Basically...you stay on them until your symptoms are gone. That could take a few more weeks or even months of nightly enemas. Only then should you consider to taper.
q
DMC2011
Veteran Member
Joined : Jul 2011
Posts : 2512
Posted 10/13/2013 2:49 AM (GMT 0)
What kind of enemas? Pred enema? I never knew they had these. Or is it corte enema? I am confused I guess.
AnnaG
Regular Member
Joined : Apr 2008
Posts : 191
Posted 10/13/2013 3:29 AM (GMT 0)
Hi thanks!
I'm in the UK and this time I got them from my Doc which is like your primary physician I believe,I not see my GI so I did not get any instructions on long to use them,and I have not been very successful with rectal meds when I've tried to use them before,firstly because I find it v painful to do and I have not managed to administer them properly and also I think because I have not persisted long enough.
They are 100ml nightly retention enemas they have 20 ml of prednisolone in them in water saline solution,I really need these ones as I have severe left- sided UC and the foam ones don't get up high enough so they did'nt seem to make any difference.These also did'nt seem to do much last time but as I said I still want to give them a proper chance this time before I start the Oral pred again I've had way to many courses of pred in the past and I find it very difficult.
quincy
Elite Member
Joined : May 2003
Posts : 33769
Posted 10/13/2013 5:08 PM (GMT 0)
Have you asked the doctor about
mesalamine enemas? Are you on any oral mesalamine at all?
q
AnnaG
Regular Member
Joined : Apr 2008
Posts : 191
Posted 10/13/2013 6:55 PM (GMT 0)
Hi Quincy thanks for your advice on the r meds I am really hoping to be successful with them this time,I did have mesamline foam enemas before and I thought at the time they agree attend things and made me sore and bleed more,I think I may be allergic but I'm not sure it could just have been the progression of the flare at any rate they did'nt seem to improve things,you don't know if there is a test to see if you are allergic to the Asa stuff I think I may be be I should also be taking 2mg
Pentesa granules but I also think they make me bleed more as the blood I pass is mostly darker thicker and with clots it makes me think it's from higher up I don't often get really red blood,but sometimes get more red blood when taking the pentasa I wish I knew for sure.
Jessa33
Regular Member
Joined : Aug 2013
Posts : 163
Posted 10/15/2013 4:04 PM (GMT 0)
Hi Anna,
The foam version of the mesalamine enemas is quite irritating for some people. I would speak to them about
the 2g liquid version as I think it is better for reaching as high as possible and there are articles on the web which suggest these have been more effective for patients in trials than the pred enemas.
quincy
Elite Member
Joined : May 2003
Posts : 33769
Posted 10/15/2013 5:41 PM (GMT 0)
I think it could be that you're undertreated. You could switch from the Pentasa granules to maybe Salofalk pills and the foam to the liquid.
Starting at the 2g liquid might be a good start, but I think using the 4g initially would be better, then taper back and use the 2g maybe for maintenance twice a week (a process to get there).
How often are you having bms. And what's the extent of your UC...throughout or limited to where?
q
AnnaG
Regular Member
Joined : Apr 2008
Posts : 191
Posted 10/16/2013 12:17 PM (GMT 0)
I think you might be right I am probably under medicating at the moment,but I suppose it is partly my fault as I am reluctant to see the consultant again I want to try and sort it out myself this time and I know going back to the consultant he will strongly advise I go straight back on oral pred and azathioprine.
I'm in the Uk so I don't know if we have the option of Salfork or what it is but I don't think I can have stronger enemas I think the 20mg ones were the only ones offered me at any rate.
But on the good side I think things have got a lot better this week end of second week of enemas,I had no bleeding all day yesterday along a bit in the evening but more mucous much less pain than last week when having bowel movements and much less blood than before during and after each movement.
I have had no D at all this time and no constipation which has been a real problem for me in the past,which I attribute to taking the psyllium seed everyday and keeping to a softer diet with no insoluable fibre or seeds whole grains etc no fizzy drinks and things that kill me when I'm all inflamed.So strangely I have no real bowel issues at all this time apart from the fact the stools are bloody skinnier and well obviously not normal I'm going x2 or x3 a day as oppose to once when I'm normal.
Like I say I'm hopeful things are going slowly in the right direction because I haven't got that level of feeling faint and tachycardia with the pain that I get when I'm really bad and the blood is certainly less.
Last night I could'nt get the full enema in again because half of seemed to come right out,which was really frustrating as its been so much better on the nights I've managed to retain most of it.
I was diagnosed with severe left-sided U C six years ago I had a scope last year when it was in remission and he did'nt mention that it had progressed any, but I do have a lot of polyps,he took some byopsies and they were all clear.
Thanks Anna
quincy
Elite Member
Joined : May 2003
Posts : 33769
Posted 10/16/2013 5:31 PM (GMT 0)
You don't actually know what's available to you. Call your pharmacy and ask about
the Salofalk enemas and what strengths they come in.
You have choices.....but do the research.
Just an fyi...it's strongly believed that 5ASA meds help protect the colon from cancer. you might want to consider the rectal meds that have a higher amount of punch and then taper them to a maintenance level during your remission time. If you don't have to go to the other meds, it might be one of your best choices...but....it's a commitment. I've only been at it for almost 25 years, cannot express how pleased I am with the outcome.
q
Jessa33
Regular Member
Joined : Aug 2013
Posts : 163
Posted 10/20/2013 8:09 PM (GMT 0)
Hi Anna,
They do have salofalk 2 g and 4 g enemas in the UK. I think they are slow to prescribe it because it is expensive but you should ask for a prescript
ion. Hope you are getting better.
AnnaG
Regular Member
Joined : Apr 2008
Posts : 191
Posted 10/20/2013 11:35 PM (GMT 0)
Thanks Jess,
My consultant has certainly never offered them as an option,but then he would'nt prescribe VSL 3 for me either because he says he dos'ent believe they make any difference so I had to persuade my GP to prescribe those for me.
I'm doing much better in the days thanks but still losing a fair bit of blood pain in the evenings but I have fine all and generally better than 2 weeks ago although I'm a bit frustrated that it's only very slowly up if you know what I mean,and just a little bit scared that when I get worse it goes serious quickly !
Take care Anna
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