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An anti-inflammatory diet as treatment for inflammatory bowel disease: research study

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Ulcerative Colitis
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Posted 1/16/2014 11:07 PM (GMT 0)
Just come across this, not had time to read it yet, looks like an SCD type of diet but also including resistant starch?

www.nutritionj.com/content/pdf/1475-2891-13-5.pdf

They conclude

said...
The study of the IBD-AID would benefit from the rigorous analysis provided by a randomized clinical trial, with evaluation of mucosal healing and assessment of change in gut flora to examine the exact
mechanism (s) of benefit

Slim chance of anyone funding a RTC I'd have thought though, with no one to profit from the diet at the end other than patients who might get better
Posted 1/16/2014 11:46 PM (GMT 0)
Thanks for posting this. I will add it to my list of articles to read this weekend.
Posted 1/17/2014 1:38 AM (GMT 0)
FWIW Barbara Olendski is my nutritionist. She is fantastic. Her team hold biweekly cooking classes for their IBD patients to help them to adhere to the diet. It is indeed an offshoot of the SCD but is modernized based on the latest research. Barbara and I talk a lot about prebiotics for example and the diet permits things like oatmeal.
Posted 1/17/2014 2:20 AM (GMT 0)
Interesting. I tried SCD and didn't have any improvement. Maybe I was unresponsive for whatever reason. I always suggest other people give it a try, can't hurt,
Posted 1/17/2014 3:30 AM (GMT 0)
A peer-reviewed article focusing on IBD diet from medical professionals associated with a medical school?!? Finally!

I think the only place these kinds of studies will come from are research universities, but those even require funding (such as via the NIH).

They may not have been able to "prove" affects on the microbiom of our gut, but it's a great first step!
Posted 1/17/2014 8:00 AM (GMT 0)
Thanks for posting
Posted 1/17/2014 11:25 AM (GMT 0)
Very interesting, i can see the only sources of carbs are those with a high resistent starch/prebiotic content such as legumes and oatmeal. Makes sense.
Posted 1/17/2014 1:07 PM (GMT 0)
Thanks for this posting this.

snip of the paper: After following the IBD-AID, all (100%) patients were able to discontinue at least one of their prior IBD medications, and all patients had symptom reduction including bowel frequency.

100% of trial participants did not have success however, some chose not to do diet modificiation.
AID stands for Anti Inflammatory Diet.

3 people who did participate in the diet had little or no success.

Three had an ambivalent or negative response to the diet, and 24 had a good or very good response to the diet, as measured by self-report of symptoms and compliance with the diet through food records. Of the patients reporting improvement, they were all able to reach greater than 70% compliance to the diet. Of the 3 patients (2 with UC, 1 with CD) with ambivalent or negative response, 2 were diagnosed with Clostridium Difficile (C-diff), and the other (UC) patient’s response is unattributable.

(underlining is mine)

I'm saving this to give to my GI next visit, not for me but perhaps he will suggest it to other patients or at least not dismiss it when they ask.

Please note however this does not mean "remission" if you follow the diet, it says "symptom reduction". For me it took a looong time and much tinkering with diet to get to the big R but I had UC 10 years at that time and had a lot to repair.
Posted 1/17/2014 1:38 PM (GMT 0)
I'm not really sure what it means that these patients were able to "discontinue at least one of their prior IBD meds", because they didn't get specific. To play devil's advocate, this sentence might really mean squat. A normal course of treatment for UC would be to give prednisone and an oral ASA like Asacol(or rectal meds), tapering back on the pred and hopefully the Asacol or rectals would keep you in remission once off the pred. So, without any diet plan whatsoever, these people would be able to "discontinue at least one of their prior IBD meds" anyway. This is one example of clever trickery to back up their points they want to make. But, I'm not saying that it's not legit either. I just wish they would have been more specific on which meds these people were on and which ones they were able to discontinue. One thing for sure though was the study seems to clearly show that most all patients could not eliminate all of their IBD meds.
Posted 1/17/2014 2:14 PM (GMT 0)
It's not unheard of for people to discontinue their medications when a diet restores the microbial balance. It's even questionable whether some of these medications do anything at all given the dismal efficacy rates in meta-analyses (see NNT of pentasa and other mesalamines). Mutaflor and other probiotics like vsl are just as effective if not better than mesalamines, so it ends up being a pick and choose thing for most patients.

imagardener2 - i'd be skeptical of your doctor accepting something like this. He's trained in a modality that favors a top down approach where the symptoms are treated as the root cause. My family is filled with medical professionals who think this way and they wouldn't even spend a second looking at it because it goes against everything they were taught in medical school.
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