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Curcumin in Combination With 5-aminosalycilate Induces Remission in Patients with Mild to Moderate U

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Ulcerative Colitis
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Posted 3/4/2015 11:41 AM (GMT 0)

Eph said...
Just found a great review of the various curcumin products Amazon sells here: amzn.com/B00JA4TLTI?tag=epswo-20

Check out the review from RWM from November 30th.


Just any FYI to anyone who clicks this link, don't buy from it. ?tag= is a referral link, so people profit from you buying something on it. Since this forum isn't about profiting off each other, I think it's in bad taste.

Googling the referral code it's just Eph giving it out on these forums.. So I'm not sure why he would want to profit off fellow people with an awful disease.

If you want to see the product click this link www.amazon.com/dp/B00JA4TLTI/
Posted 3/4/2015 1:49 PM (GMT 0)
Yes, my bad. Sorry. I do think it is an excellent review and wanted to link to it. Debated whether to put the referral in, and clearly made a bad choice. Sorry.
Posted 3/4/2015 8:51 PM (GMT 0)
I appreciated the link to that particular review because it went into a lot of comparison and detail about different manufacturers of curcumin. I never knew that giving a link equalled a payday although I have signed up for AmazonSmile so the non-profit I volunteer at gets pennies whenever I buy on Amazon.

Perhaps HealingWell could do the same link and we could payback some of what we have gotten from this great forum.
Posted 3/5/2015 3:49 PM (GMT 0)
I have Crohns and have been taking curcumin for a couple of years. I think it has helped keep me in remission and helped a bit with joint pain. I take the Physiologics brand...1000mg tablet that also has black pepper extract.
Posted 3/5/2015 4:09 PM (GMT 0)
Sparkle -- you may want to look at the first review for that Physiologics branded curcumin. Sounds like it may not have as much curcuminoids as some of the others...
Posted 3/7/2015 10:35 AM (GMT 0)
I was wondering if Curcumin helps to a certain extent for UC because of its antibacterial effects. According to google there seem to be several studies that prove the antibacterial effect.

According to the signatures of many posters in this thread, Curcumin is often taken in combination with probiotics (as do I). This makes me ask how you take your Curcumin and probiotics in order to avoid the negative effects of the Curcumin on the probiotics? Since it is recommended to divide the daily dose of Curcumin into smaller mealtime doses, it is quite difficult to make sure there's a lot of time between the intake of the Curcumin and the probiotics. Or do you think they do not interfere much?
Posted 3/8/2015 11:02 PM (GMT 0)
I believed curcumins worked when I bought it and took it, but in reality it was just to make myself feel better about wasting money buying it.

I tried juicing organic turmeric, taking those fancy pills with pepper to "enhance absorption", powders, more pills.

It probably won't get you out of a flare or reduce your symptoms, but it will make you feel like you're trying.

This Medz guy doesn't sound like a reliable source of claiming curcumin works for UC
Posted 3/12/2015 11:00 PM (GMT 0)

fightUC said...
This Medz guy doesn't sound like a reliable source of claiming curcumin works for UC

I'm not a source. And you're certainly not a source.

Patients in the curcumin group had significantly lower disease activity index and endoscopic index scores at six months than patients in the placebo group. No serious side effects were reported. The results of this systematic review suggest that curcumin may be a safe and effective therapy for maintenance of remission in ulcerative colitis when given as additional therapy with mesalamine or sulfasalazine. - http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0049365/

Curcumin seems to be a promising and safe medication for maintaining remission in patients with quiescent UC. Clin Gastroenterol Hepatol. 2006 Dec;4(12):1502-6. Epub 2006 Nov 13. PMID: 17101300

Curcumin protects against chemically-induced colitis in the mouse model. - Results suggest that curcumin could possibly have a protective role in ulcerative colitis probably via regulation of oxidant/anti-oxidant balance and modulation of the release of some inflammatory endocoids, namely TNF-alpha and NO.Am J Cardiol. 2009 Dec 1 ;104(11):1551-5. PMID: 19932791

Curcumin prevents the development of experimental colitis. In conclusion, the development of DSS-induced colitis was significantly attenuated by curcumin. Being a nontoxic natural dietary product, curcumin could be useful in treatment of IBD patients. Dig Dis Sci. 2007 Nov ;52(11):2993-8. Epub 2007 Apr 11. PMID: 17429738

Curcumin ameliorates experimentally induced ulcerative colitis.- In conclusion, we suggest that inhibition of p38 MAPK signaling by curcumin could explain the reduced COX-2 and iNOS immunosignals and the nitrite production in colonic mucosa reducing the development of chronic experimental colitis. Int Immunopharmacol. 2007 Mar ;7(3):333-42. Epub 2006 Dec 18. PMID: 17276891
Posted 3/13/2015 1:27 AM (GMT 0)
As Medz and others have posted, there's plenty of evidence that curcumin can be effective. It works for me. It won't work for everyone but I suspect more UCers would get results if they took larger amounts, 2 grams or more per day.

I'm not usually an alternative medicine person (yay for vaccines!!) but I tried curcumin because it met my two criteria: 1) there were peer-reviewed studies showing efficacy and 2) it's very safe, with zero dangerous side effects, even at high doses. To me, this makes it a good FIRST option to try - before Remicade,etc. - if 5ASAs don't work.

I wish more folks here would give it a try for at least 2-3 weeks at a high dose, with a reliable brand.

The only down side is it can get expensive. At 3 grams per day it's not bad but when I was flaring and took 6 grams per day, it was $80 per month and not covered by insurance. But well worth the expense.
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