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Blood Test Results Help - UC Related of course.

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Posted 8/31/2015 2:59 PM (GMT 0)
So 16 years with UC
Flare since November
Blood etc

Had blood test got results - can anyone help me decipher this:

White Blood Count - 9.3
Red - 4.91
Hemo - 140
Platelet - 327
Mvp - 10

Sodium - 141
Potassium - 4.2
Chloride 104
Creatine 96
Glucose 5.4

Lipase 116
GGT 15
Alkaline Phosphate 101


39 Years Old - Male

Feeling like garbage - 2 mezavant 2x a day seems to do nothing, toilet 20x a day all liquid bit of blood.
Colonoscopy in Feb no scar no polyp - but diagnosis of Pancolitis. So after 16 years is this normal is what I'm trying to ask..... thanks in advance for any input.


V
Posted 8/31/2015 4:29 PM (GMT 0)
Did your results not come with reference ranges? These all seem pretty normal to me.
Posted 8/31/2015 5:12 PM (GMT 0)
You sound under medicated for someone going 20x a day with pancolitis. Wondering why you are not on other meds?

Your bloods should come with reference ranges? They look OK but depends on the units your lab is using.

You're missing CRP and ESR there which are inflammation markers
Posted 8/31/2015 5:34 PM (GMT 0)
Ok let me check, thanks for reply London, Mar .. I haven't been given the option of any of the big guns

White Blood Count - 9.3 Range 4.0 - 11.0

Red - 4.91 Range 4.20 - 5.80

Hemo - 140 Range 135 - 170

Platelet - 327 Range 150 - 400

MCV - 10 Range 82 - 98

Sodium - 141 Range 135 - 145

Potassium - 4.2 Range 3.5 - 5.0

Chloride 104 Range 95 - 107

Creatine 96 Range 60 - 115

Glucose 5.4 Range 3.6 - 11. - this was with no fasting

Lipase 116 Range 0 - 393

GGT 15 Range 15 - 80

Alkaline Phosphate 101 Range 30 - 135


CRP - does this stand for Coagulation? if so it is 0.9 with a range of 0.9 - 1.2

ESR - ? Don't see anything on here with that acronym? Called anything else?

Appreciate the help...

V
Posted 8/31/2015 5:47 PM (GMT 0)
Ahh ok I see the CRP is under Serum Proteins : C reactive Protein (high sensitivity) - 3.7 <5.0 mg/L

ESR - I don't see .... maybe under a different heading?

V
Posted 8/31/2015 6:01 PM (GMT 0)
What kind of doctor have you been seeing? Surely you didn't start having 20 BM's per day just overnight, and you have been flaring since November, diagnosed with Pancolitis since February, and no one bothered to change your treatment plan? Obviously 4 Lialda per day isn't cutting the mustard. Either you or your doctors or both have let your condition get out of control, which makes it very hard to treat once it gets that day. Lialda is generally prescribed to take all at once instead of twice per day. The blood test you presented looks more like it came from a PCP as, for the most part, none of those numbers have anything to do UC. Someone needs to get serious about treating you or you might as well just schedule surgery now.
Posted 8/31/2015 6:39 PM (GMT 0)
Your blood test results look very good, with only MCV being out of range. So, I don't think your answer lays within that blood test. The MCV is often compared to MCH ir MCHC, if they're all out of range you might have anemia.

Have you had stool tests to look for pathogens like cdiff? As cdiff can cause 20+ bms a day and be unresponsive to uc medication.

Mezavant (a 1.2 gram pill x 4 pills a day = 4.8 grams) dosing is the maximum. You aren't on any meslamine suppository or enema , they might help heal you. But at a 20+ bms a day retaining them might be impossible.

I'd say you need to be on steroids (prednisone) and a stronger uc medication like immunosuppressive medications (Imuran, aza, 6mp). You're not aggressive enough with you medications to tame your uc flare. Time to pull out the big guns and get serious.
Posted 8/31/2015 7:30 PM (GMT 0)
Yeah Gary, I totally agree, for about 14 out of the 16 years I didn't take any meds... just a lot of asacol back in the day but that just stopped working after 4 months or so... The spinach sunbutter diet helped me for years - doesn't seem to anymore. I didn't see the GI for a looong time maybe every 3 years fo the colonoscopy for colon cancer check. Just recently - last 2 - 3 months its out of control, but def flaring since november.

Started back on the Lialda - but seems to have made things worse - but maybe worse before better? You think 4 at once maybe before bed is better than 2, 2x a day? Everything goes right through me so I don't even know how this will help... maybe if it gets absorbed a bit at night. I find 80% of my BM are in the morning. In a flare like this they are all day long though.

I do have a call in to see GI and reasses over the next week or two. Thanks for all the input.

V
Posted 8/31/2015 7:35 PM (GMT 0)
I think you mean 'creatinine' which is the metabolite for creatine.
Posted 8/31/2015 7:40 PM (GMT 0)
Yes sorry was thinking of the work out powder when I wrote that.
Posted 9/1/2015 4:22 PM (GMT 0)
Definitely sounds like you need to get back to GI for proper testing, don't put up with this - with years of UC we can put everything down to UC so do make sure your stool is tested for all pathogens and parasites to rule out any infection. Your inflammatory marker, CRP isn't high, so ask for a fecal calprotectin test which looks for inflammation via the stool. ESR is just another marker, not necessary really.

Your MCV seems very low, not chance it was 100? I'd ask for a retest on that and further iron studies if that was not an error. I'm not an expert on MCV, mine was high while on Aza/6mp which I'm told is common on those drugs, otherwise high is a sign of B12 or folate deficiencies possibly but I don't think low is.

Sounds like you need to be stepped up to the next strength of drug. Hope you get some relief soon.
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