Low Dose Naltrexone

Do a search of our forum and you will see LDN all over the place. Mainstream medicine has never encouraged it but grass-roots word-of-mouth is reaching a critical mass.

www.lowdosenaltrexone.org/gazorpa/History.html

Naltrexone in substantially lower doses (Low Dose Naltrexone) is showing great promise as a treatment for multiple sclerosis, Crohn’s disease, AIDS, rheumatoid arthritis, celiac disease, CFIDS, lupus, and certain forms of cancer.

Unfortunately, obtaining FDA approval for LDN will not be a straightforward process. Since naltrexone is now a generic drug, no pharmaceutical company currently holds exclusive manufacturing rights. No company is eager to fund an expensive clinical trial for a drug that will make them so little profit.

However, even without governmental approval or corporate support, LDN is gaining significant grass-roots attention among patients and doctors. The exchange of research information over the internet has greatly accelerated the recognition of the off-label use of LDN.

I think it's working for me, or I'd be flaring right now. Even though I'm having issues as we speak, lol.

Planning on upping my dose.

John,

I am a strong proponent of LDN because it put me in remission, it's cheap (around $30-50 per month), and has virtually no side effects.

There a post on it on the UC Resources page that explains it, with links too.

I found LDN by accident whilst doing research.

The traditional meds did nothing for me, and then I became intolerant of the mesalamines.

3 days after I started taking LDN, my bleeding was dramatically decreased, and within 7 days of being on LDN it stopped completely.

I have been in remission ever since.

BTW, there have been 2 published studies that have shown high remissions rates in Crohn's patients. Both studies were done by Dr. Jill Smith of Penn State. You can google the studies.

 

I stand corrected- InSoFla is correct that there are published studies showing on pubmed for LDN and IBD- well, I found one anyway, for crohn's:

www.ncbi.nlm.nih.gov/pubmed/17222320.

It is a tiny study but it is something. I certainly agree LDN is something worth trying. That said, many, myself included, noticed no definite benefit from it. But it's cheap and I dont think it hurts to try. I certainly appreciated InSoFla's sincere effort to help me duplicate her success- didmt work for me whereas surgery worked like a charm, but at least I could rest knowing I tried.

so jonny m , ya gonna give it a whirl ? if my current status begins to decline, I will definitely be giving insofla a call !

Josh,

I'd be very surprised if your GI wrote you script for LDN.

As open minded as they generally are about Big Pharma drugs, they are just as closed minded about LDN.

Hopefully your GI breaks that mold!

Let us know.

Rebel,
Thanks for the question.
When I use the term Remission, I do mean Total remission.
No bleeding, no cramping, no urgency, no diarrhea, no pain, no distention, no bloating.

Going 1 or 2 X per day, normal bm.


Let me know if I can be of any other help to you.

InSoFla said...
Rebel,
Thanks for the question.
When I use the term Remission, I do mean Total remission.
No bleeding, no cramping, no urgency, no diarrhea, no pain, no distention, no bloating.

Going 1 or 2 X per day, normal bm.


Let me know if I can be of any other help to you.

hi insoflo,

oh! thats good to hear.

i do have one more question though, in your signature, u listed being on a paleo diet as well...

despite being on ldn, would going on a varied diet with fiber etc, bring you out of remission? like loose stools etc

also did u experience any bumps on the road to remission with transdermal ldn?

thx for taking the time to reply

:)

Rebel,

I eat a healthy diet - Paleo, almost no grains except for occasional rice.
But I do cheat once in a while - that means a cheat per day for 2-3 days, while taking "cheating" precautions.
I would never go back to my old lifestyle of non-Paleo and gluten, and cow dairy - because I know it causes major inflammation to whatever is the weakest point in the body. In my case it's UC, but if my DNA were different, it could be pulmonary or cardioligical.

And science tells us inflammation=disease, so why tempt the Gods?

As far as bumps on the road to remission, yes it was simply a matter of finding which form of LDN worked best for me. Different forms have different success rates on different people.

Hope this helps.

oh and btw, i was asking about your detailed experience with ldn because, i am not able to get transdermal ldn in my country, and was looking for ways to self make a topical ldn with the 50mg pills,dmso etc.

but realised i didnt want to make myself worse off trying what could potentially be dangerous.

was also worried about the effects it has on our brains hormonal systems etc. sleep and so on.
am already consciously depressed, dont wanna mess with hormonal systems that may sent me over the edge.

hey isf -

just wondering if your siggy is current ???? asking because it seems like as continue to feel better, my body is asking for less in the supplement department - which is just okie dokie with me and my wallet

studnomo

Rebel1992 said...
hey,
to insoflo and others who have had ldn work for you.

when you mean that ldn has induced remission inyou...

do you only mean reduction of bleeding and pain ...or does your remission involve proper bowel movement etc.

and any other new problems that you have expereienced while on ldn

thx

Reduction of all symptoms. Zero inflammation. I can have normal movements with no symptoms whatsoever. I only had nausea, lose of appetite, and some sleep issues while upping my liquid dose. I've been able to eat wheat and other processed foods, too.