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UC and UTI

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Ulcerative Colitis
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Posted 12/22/2014 7:49 AM (GMT 0)
At my last appointment with my doctor, he mentioned I think that Apriso (or maybe just meds treating UC in general) can cause urinary symptoms. I had a UTI about a week before that appointment and now I am experiencing symptoms of one again..making that two infections in the last month and a half. Has anyone ever experienced some kind of relationship with treatment and urinary symptoms?
Posted 12/22/2014 1:39 PM (GMT 0)
I was on 5 different 5ASA's over the course of 22 years and I have chronic UTI's. I also have a standing prescription for Macrobid because of this. I also have chronic idiopathic microhematuria (blood in the urine). But I don't correlate any of my UTI's with my UC treatments. I have seen numerous urologists and one told me that some people have a natural "stickiness" around their urethra that tends to collect bacteria which in turn can cause UTI's. Also especially with people with Uc, who has D regularly, no matter how well you wipe,there still is fecal bacteria in your underpants which also cause UTI's in susceptible individuals.
Posted 12/22/2014 1:39 PM (GMT 0)
No. Apriso is an anti-inflammatory medication that treats the lining of the large intestine. It will not effect your bladder and cause an uti. Immunosuppressive meds used for uc do make one more prone due that immuno suppression (e.g., 6mp, imuran, remicade, humira).
Posted 3/28/2016 11:17 PM (GMT 0)
@Red_34:

Are you still having a problem with chronic UTI's? I had one a year ago that cleared up quickly. A couple of weeks ago, I started having symptoms that were extremely painful, and much worse than a year ago. I went it and was told I had a UTI and was given macrobid and the pyridium for the pain. After a week of the antibiotics, the pain went away and symptoms improved, but now I'm having pressure and urgency again.

I also take Apriso, so I'm not sure if there's a connection there. I'm also in my early 40's now, so age could have something to do with it I guess. I've only had 3 UTI's in my life that I can remember.
Posted 3/29/2016 1:16 PM (GMT 0)
Because of our anatomy, females who have UC are much more likely to get UTI's. Something about that repeated bathing of the area proximate to the urethra with the E. Coli always present in feces. Take extra care to wipe from front to back, to help prevent contaminating your urinary tract.
Posted 3/29/2016 3:20 PM (GMT 0)
The UTI's I have had were cultured and are strep infections, not e-coli, so wiping really doesn't seem to be the issue in this case.
Posted 3/29/2016 11:10 PM (GMT 0)
Yes, I still get chronic UTI's. And I still have a standing prescription for Macrobid. My GI told me that since I am on Remicade that I would be more prone to opportunistic infections such as UTI's. Combine the Remi with a sticky urethra and I get the double whammy.

If you are sexually active, I highly recommend you urinate after intercourse, always wipe from front to back and if you have any Macrobid, take one before bedtime. Also, drink a LOT of water. Since doing this, my UTI's have decreased.
Posted 1/10/2017 10:43 PM (GMT 0)
I have been on Apriso for my UC now for almost 2 years. In the last 6 months, I have been diagnosed with 4 UTI's. I assumed it was from the UC being extra messy, but each time, the cultures came back with no bacteria. Antibiotics seemed to help with the kidney pain, but made me start questioning the Apriso with no bacteria in the cultures. Last week, I stopped taking my Apriso and antibiotics too and going to try to control the UC with pro-biotics. I plan on monitoring the UC symptoms for a little while before I contact my Gastro Dr. So far, I'm taking 2 capsules of pro-biotics a day and everything seems to be normal without any UC symptoms. I also figure, pro-biotics is still cheaper than Apriso. The UTI symptoms were not typical, I had lots of pain on my left side towards my back, like a typical kidney pain.

Post Edited (J3randiJo) : 1/10/2017 4:04:52 PM (GMT-7)

Posted 1/10/2017 10:51 PM (GMT 0)
I would get very uncomfortable bladder symptoms similar to a UTI when severely flared up, but would test negative for UTIs, cystitis etc.

It was my inflamed colon pressing against my bladder that was causing the unbearable discomfort. I learnt that for me, when I got this sort of bladder discomfort it was a sign that my UC was pretty bad and I was close to being hospitalised.
Posted 1/11/2017 11:57 AM (GMT 0)
I have UC and painful bladder syndrome (previously recurrent UTIs and still very susceptible) and the thing that I found most helpful for me was D-mannose - it's a natural sugar and how it works is the e.coli (cause of 90% of UTIs) preferentially binds to it over your bladder wall and you excrete them. It also had a really soothing effect when I have symptoms, and I take a big glass of water with it in it before sex and after to flush any bacteria out.
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