Prednisone not working

I have been taking 50g Prednisone for 2 weeks, the first couple of days seemed to hit the mark, and the bleeding receded. The last six days have been difficult; I feel like I am now not getting any better at all, on rising in the morning the toilet is full of blood with no proper bowel movement, not even 'rabbit droppings' I'm just not Pooping. The crux of my problem is food..if someone had told me a year ago a tomato, cucumber or the wrong lettuce leaf, could make someone very sick I wouldn't have believed them.

I am sulfite, salicylate, oxalate, histamine intolerant with amine issues and gluten and dairy intolerant too, this means my diet currently consists of a total of around 15 foods, which results in my not being able to eat the right foods, to get things moving correctly. If I stray off the good foods and cheat I become VERY ill, a good example of this, was a mildly spiced dish the other day, which changed my voice from normal to hoarse and raspy within an hour. I have an epi pen as there is a slight chance of an anaphylactic attack due to these issues.

But, back to my problem, the last three nights I have been up passing blood and mucus, trying not to strain, and today I took something for constipation and managed to go normally, this was the first time in a week! My colon hurts, and I seriously nearly passed out today.

I don't know what to do this evening if I am rolling around in pain in the middle of the night. I think it's probably just constipation. However, I don't know for sure. I don't like the hospital here, people don't go unless your desperate, accidents happen, people die, but I wonder if I am seriously getting worse. I think I need another Med on top of the Pred, which is a concern as my GI is back a week on Thursday, and so I will have to wait.

I have become worried about the suggested azathioprine as I am just full of allergies, and feel it probably won't be the best for me, maybe the biologics are the thing, but I would really like to have the opportunity of trying LDN which might be the key, for someone like me, but not sure what I am going to do in the short term until I see my GI.

Any advice or ideas would be most gratefully received!

how long have you been taking the molybdenum and why ?

here's one thread i found - might be helpful >


forums.phoenixrising.me/index.php?threads/who-has-experienced-an-adverse-reaction-to-molybdenum.21686/page-2

when has your stool been tested last?

you need an exit strategy for prednisone

Want some nitroglycerin? Lol!

It's hard not to get carried away; but you may not be in pain this evening. You may be fine! If it is constipation, it may be easing given you've had 3 bm's.

If you do have pain, what has helped in the past?
( waiting for a GI is agony when distressed.)

Could you try some Miralax to reduce constipation? It has helped my when I've struggled. And I've been really diligent with bland diet.

So sorry to hear you're struggling. What's the long term game plan?

Like you, I'm allergic to a lot. So adding more medication is always a scary prospect.

Gee, each of our systems is so different in terms of drugs.... I had a very bad experience with 6MP - even at initial low dose. And I'm allergic to all mesalamines (as well as sulfa, penicillin, etc).

Sounds like you are so very uncomfortable. Trying to get to a dr ASAP seems like the wisest next step. Hang in there!

Azathioprine and 6MP are slow acting drugs -- they can take 3 months to start having an effect. I believe that some of the biologics can start working more quickly. You should talk to your dr.

Are you using any rectal meds? If you can't tolerate mesalamine, what about a steroid foam or enema? Rectal meds usually help pretty quickly.

Hmm. I trust you know what you're doing with diet.
For my body, I couldn't eat most of what's on your list when I was flaring badly. I gave up on nutrition and just went for bland chicken broth, chicken & rice.

Want to try the Orgain vegan vanilla shake? Once I found them, I was able to live comfortably for months. In fact, I still drink them even though not flaring. (You can order online.) You can show your nutritionist the ingredients, if you google it - there's a photo online.

I agree about potential relief from hydrocortisone enemas, especially in more distal area. You should be able to tolerate them well, from what I recall of your history.

Remicade was surprisingly fast-acting for me. I would do it again (even with the adverse effects I had) because it stopped a disabling severe flare & gave me well over a year of entirely quiet UC symptoms. I wish I had begun it earlier. I had delayed the start about 9 months because I was afraid of it....

Hang in there. This is temporary.

Content...thanks I will have a look at that Orgain milk shake, and maybe I should be really cutting back on more for a while...weirdly I couldnt eat rice for a while, I mean who can't eat rice? Anyway I seem to be able to kind of tolerate it again and its a low salicylate food so i think I am going to try more of that and a bit less of some other things over the next few days.

Stud...Yeah, I know, but being totally upfront and honest, I cheated!! salicylate intolerance is a cumulative thing, your levels become high, (rather like a bucket becoming very full), the aim is to stop all foods high in salicylates and to reduce the level in your bucket thus enabling you to start trying new foods. Unfortunately I succumbed to chocolate a couple of times, I couldnt help myself and I believe that brought my levels back up making 'my bucket' full again...its hard!!! I have got myself together now and I am not cheating, but I am dissapointed in myself, because if I had being a bit stronger I might have have been on the next level of food. Obviously I havent told my dietician I cheated, it is embarresing, it is difficlut to describe the torture I feel not being able to eat anything, it is a form of torture almost....

I agree, it is about making hard choices.

I think for me I really had no idea how far I could go with regard to having the odd treat without being ill, and of course, now I know....not far!!