FMT while flaring?

I have done a lot of research on this but the opinions seem to be mixed so I thought I would ask here. I want to try FMT as a last ditch thing before getting surgery. I have failed all other treatments and am currently flaring with 5-6 BM's a day and blood. My doc isn't too keen on the idea as she says I will go septic and end up in the hospital. I tend to follow her advice but I feel I have to give this a shot before yanking out my colon. I have a healthy donor and would get him tested of course. So has anybody here tried FMT while in a flare? Any success? I am interested in hearing what you folks have to say about this. Thanks guys!

I too was flaring severely when I first underwent FMT. Was going 15-20 times day, lots of blood etc and turned me around in a few days. Since then, for a number of years whenever I had a flare I had an FMT. It doesn't seem to be a risk, even in those who are nearly dying of C.diff. Hope that allies your fears somewhat.

I tried FMT after having C difficile. I just didn't want to run the risk of it returning, as I knew from experience that it was a killer!!

Anyway, before the FMT my stools were like rabbit poop with a tiny bit of blood, after the FMT I improved every day and have not seen any blood since. The most exciting thing about the whole experience was seeing my poop change overnight!

This is our status and feedback on FMT.

Initial FMT was done in a clinical trial. Prior symptoms was 30 times a day with diarrhea and heavy blood. Post FMT, same day blood, and frequency stopped.

We did home FMT almost 60 for about 15 months. After 15 months, no matter how many times we did FMT blood continued. After that, we started LDN and that seems to be helping a lot.


FMT is a must do for everyone who have not tried.

I think most people do it while flaring. Your doctor may be a bit over-dramatic saying you would go septic, she knows more than I do of course, but I don't know if I've ever heard of that happening to anyone (you will be the first since i said this, sorry). My GI never said that to me, but she did say in order to get it to the areas you need it, you need to infuse a large quantity, and that while in a flare-up, you're usually not able to retain it well enough to get any benefit. I've seen a lot of people have luck, so I don't see a reason not to try it if you're not squeamish. I didn't bother because I didn't think I'd be able to retain it, and I don't have a good donor - nor do I have the resources to get a donor tested. Seemed like a lot of trouble. I love my j-pouch.

I've asked quite a few GIs about it, since I've been to 4 or 5 during the course of my UC treatment. A few mentioned that FT doesn't help everyone, and in fact, it has made many people's condition worse - but in the case of surgery being on the table, you may not be too concerned about getting worse.

FMT = shooting a freinds poop up your butt - surprised you haven't heard of it -

The abbreviation FMT is Fecal Microbiota Transplant. It takes stool from a healthy donor and transplants it into us with a pill, upper endoscope, or sometimes a colonscopy or enema. Those of us with UC have really wacky bacteria makeups within our intestine. We have very little bacteria diversity when compared to a healthy individual. We have higher ratios of bad bacteria. Whether our wacky bacteria makeup is a cause of UC or a symptom of UC is up for debate. However, getting bacteria from a healthy donor can help us in some cases. The research shows it good for c diff, and for UC it has mixed results. Some say the methods varied and produced inconsistent results. There's some clinical trials ongoing but at this point at least it isn't a standard UC treatment. More expiremental. Hope of results should be measured as such.

New GC Hotel has been up for 30 plus years,everything is a mess traffic wise in Nassau.Ive had many more good yrs with my UC.Have had it since 85 and only been flares here and there since 08.We all react differently with treatments,some may work for u but not me.I have never worried about what to eat in all years I've had it.My normal diet isn't terrible,always been in decent shape 6'5-230-58 yo male married with 3 kids-21yo-19yo-16yo they keep me young-good luck

st_uc said...
@WorriedUCer : FMT worked for us for 15 months and now when I get a flare, it does not seem to help.

Does FMT help you even now?

St_uc: FMT helped me brilliantly at first. I was in an 8 month flare (my longest) and was bleeding profusely, 15-20 stools per day (if you could call them that) and honestly felt as though surgery was my next option. I underwent FMT (with the antibiotics first) and had a good result with the antibiotics, followed by an amazing result with the FMT - it pulled me out of that glare in 2 days. I then relied on FMT as my sole treatment for the next 5 years or so and it pulled me out of a flare each time, nothing has ever worked to pull me out of a flare like that. Then I got a new donor (my partner) and the first time I had an infusion I started getting really bad dizziness that same morning, and in the afternoon I lost my vision, and suffered a transient ischaemic attack. I suffered from dizziness from that day onwards and they eventually diagnosed antiphospholipid syndrome after I had a major stroke. There are some studies that suggest that antiphospholipid syndrome may be caused by the gut bacteria. Since then I've been too scared to try it, my fear is just too great now. I still think infection is the biggest risk with FMT, and not just the ones we know, but it's the diseases that have no known cause that worry me the most. Say you have a donor that develops multiple sclerosis in a years' time, those are the things I worry about, is it transmissible, and can you provide it even if it is?

This is an old post from 2-years ago, so I doubt the original posters will get back to you. There are no rules regarding using FMT. If you're worried then wait.