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Getting through flare without oral prednisone possible?

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Ulcerative Colitis
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Posted 4/11/2018 1:21 PM (GMT 0)
I really don’t want to take the oral prednisone.

I started rectal steroids 2x day last Friday, 4.8 grams of Lialda and mesalamine enema 1 x day.
I’m not
Running by to the bathroom at all and there is very little pain. Even my joints feel better.
I’m not going to the bathroom as much as I should either though and when I do go it kind of rushes out and is very soft.
I have seen some minor blood.

Do you think I can get through this without oral prednisone?
Posted 4/11/2018 2:46 PM (GMT 0)
So, you're at day-5 of rectal steroids and are doing better. I'd give the rectal steroids 2-3 weeks and then reassess whether you're at 100% or not. If not, consider oral steroids. Orals are generally better at severe inflammation, whereas rectals are better at mild to slightly moderate inflammation. Sometimes you can avoid oral steroids, other times they are necessary, try, wait, and see. Let us know how it goes, and good luck!
Posted 4/11/2018 3:05 PM (GMT 0)
It sounds like there is a chance, but it takes some patience, and you need to stay on top of it. Better to take steps sooner than to let things progress to a bad state. The problem with prednisone is that it's temporary and ultimately you need to find something that works without the prednisone. There is also Uceris to consider since it sounds on the mild side.
Posted 4/11/2018 4:02 PM (GMT 0)
Absolutely! What this tells me is that the inflammation is receding in location.
You will have to taper the steroid enemas, but maintain the mesalamine.

Definitely make it a process pf patience...you aren't in the category of needing prednisone oral.

Keep us posted, and just go with the process. Think tortoise snd the hare....👍😁

q
Posted 4/11/2018 7:13 PM (GMT 0)
Thanks for the post. I'm really curious about this too. I am extremely (like over the top) sensitive to the psychiatric effects of oral pred and doctors don't really seem to get this.
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