Uceris not working and I’m tired of this

Sorry to hear you're still struggling. Yes prednisone is next and a lot more potent than uceris is. Uceris is only good for very mild inflammation, unfortunately. Sounds like you have a real doozie of a flar...

For me it was work Budeo foam.
Maybe sometimes i can not hold inside. Last time firstly i used salofalk suppositories i can hold much easier then after 3 -4 times i could change budeo foam which is much stronger...
But not easy...sometimes its bettwr sommetimes it s worse with foam...
For me it is also working with other thing.8 mg medrol recently)

Hi,

Uceris did not work at all for me

Honestly, Prednisone is a nightmare. It made me retain so much water and made my feet so dangerously swollen, I actually have really deep awful stretch marks on the TOPS OF MY FEET and it blew out some veins around my ankles. I personally avoid it at all cost.

Ask your doctor about Tacrolimus (Prograf), it's a pill biologic commonly used for people undergoing organ transplants, to ensure their immune systems don't cause the body to reject their new organs. I had zero side effects and it worked GREAT.

Also, don't feel too bad about the Uceris not working for you. It's more so used to calm the less severe symptoms of UC. It's a mild band aid, that's all. If you're having heavier issues, I'd ask for Tacrolimus or maybe Pentasa. Maybe a combination of both, since Pentasa could take a while to build up in your system.

IntestinalWasps said...
Honestly, Prednisone is a nightmare. It made me retain so much water and made my feet so dangerously swollen, I actually have really deep awful stretch marks on the TOPS OF MY FEET and it blew out some veins around my ankles. I personally avoid it at all cost.

Ask your doctor about Tacrolimus (Prograf), it's a pill biologic commonly used for people undergoing organ transplants, to ensure their immune systems don't cause the body to reject their new organs. I had zero side effects and it worked GREAT.

Also, don't feel too bad about the Uceris not working for you. It's more so used to calm the less severe symptoms of UC. It's a mild band aid, that's all. If you're having heavier issues, I'd ask for Tacrolimus or maybe Pentasa. Maybe a combination of both, since Pentasa could take a while to build up in your system.

In my opinion, Tacrolimus is like dropping a nuke on a possibly mild situation in this particular case. This person has never even gone beyond the first tier of meds it sounds like. Tacrolimus suppositories might be a good option if she can insert them without too much pain from the fissues

I tried to avoid pred by starting simponi, & maybe that's an option if you're open to biologics. That or 6mp, but you would need a bridge with 6mp/imuran since it takes a long time to work.

Prednisone has worked wonders for me. Some side effects (acne, slightly swollen, slight irritability, weird energy) but all those pales in comparison to my flare ups and Pred has been incredibly effective in bringing me to remission.

Thanks you all for the advice and kind words. I called my GI this morning and heard nothing back. I’m hoping I’ll hear back tomorrow. It was so disappointing, I waited all day. I cried all the way home, I’m just tired and struggling so much. I just started a new job and I have to work. I hope I hear back tomorrow, if not I’ll probably go to the ER after work. I hate going there and try to avoid it at all costs but I guess it is what it is

I hate prednisone, I get bad palpitations, can’t sleep, gain weight, my teeth hurt. But I’ll do anything at this point. If they want me to start biologics that’s fine too!

Will look into the prograf

Can you ask to speak to one of the nurses at your GI office? Usually they'll call you back quicker than what an actual GI would.

For me probiotics cause me to flair. I tried them all and they all make me feel terrible. Less is more for me it seems. I can’t even do yogurt because if the probiotics in them. It took me a while to figure this out but I eliminated everything but my meds and ate literally the same food for 10days to figure this out. I Initially kept thinking what did I eat that is making me worse? In the end it was the probiotics that caused an immune response as if they were invaders. It was especially bad when I used vsl3.