So long, Remicade - Hello, Entyvio! (Any advice?)

Thanks again to this awesome group - you have all been so helpful and supportive over my past 18 months with UC!

So despite a round of tacrolimus suppositories (which DO help me, far more than prednisone ever did) - I'm still flaring while on Remicade, since February. It gave me a few months of partial response, and a few months of remission, but that's it. I have high drug levels, no antibodies, and doing 4 week infusions - so it's time to move on.

GI (who is AMAZING btw, highly recommend Mass General if you're in the Boston area!) is recommending Entyvio next based on the success rates they have seen in their practice and good safety profile *so far*. If anyone has pointers for starting Entyvio - which looks like next week - please let me know!

Thanks - my fingers and toes are all crossed.

Entyvio was really easy for me. Quick infusions, no side effects. Best of luck to you both!!

Entyvio has worked wonders for me. It's slow acting, but it's been excellent. My only issue is that my doctor took me off of my bridging medication a little too early (oral tacrolimus) which caused me to flare a little bit again.

They put me on Uceris to tackle the inflammation. I stopped after maybe a month and a half of it. I'm 100% leaning on Entyvio now with zero symptoms. I've been on it since February.

Zero side effects, I must mention. The first few doses you'll have will be "loading doses", which are higher doses of the medication itself. They might make you feel a little slow and tired, but after those, you're in the clear.

A nurse comes to my house and administers them. We watch Golden Girls together as I work from home on those days, LOL.

Been on Entyvio since March of 2017! It's worked great for me and I've been in symptomatic remission for over a year. It really worked pretty quickly for me and I was off the prednisone and having only a few symptoms by 4 months. That might seem like a long time, but it went pretty quickly with a decrease in symptoms.

I hope you're also blessed with a quick response!

The facebook link doesn't work. Although you shouldn't be sharing it here anyways (I would've removed it if it worked, rules and all).

Thanks, Hugo! I did get a good few months' remission once I increased my infusions to every 4 weeks, but then hit a flare in February and have been up and down ever since. Tacrolimus suppositories have helped but can't be used as a maintenance med, and I don't respond adequately to prednisone - so Entyvio it is.

Thank you so much for the encouraging words - I hope Remi continues to do a great job for you!