Entyvio

My GI doc wants me to start Entyvio since I cannot tolerate any of the Mesalamine products. I am very leary of the Entyvio.. Just wondering if any of you have tried this and your thoughts on it’s efficacy, side effects. Etc. Thanks in advance.

Thanks Kevin! How long did the rash last and how soon did you notice an improvement with your UC?

On Entyvio 2.5 years. Only side effect was a minor rash on my forehead for a few months which I guess was Entyvio, but can't be sure. It went away.

Improvement was slow, but assisted by hydrocortisone enemas. Noticeable improvements in a few months but continued to improve over a year. It took me from "moderately severe UC" (blood in stool every day, 5-10 bms per day) down to mild proctitus (no blood, still some issues with urgency). General health improved. I had lost 30 pounds in a few months, and I slowly gained most of that back.

I recommend it. Seems less risky than steroids or immune suppressants like Imuran or 6-MP.

Have been on Entyvio for over a year and will have my 10th infusion next week. No issues at all -- except for an increase in headaches which may or may not be related to the entyvio. Over all, though, I'll take the headaches rather than UC symptoms. I am in remission symptomatically. I was steroid dependent when I started my infusions and was able to wean off them for the first time with no issues by infusion #4. I too was worried about it but felt I had no choice and I'm glad I did it.

As I've mentioned previously, I started Enytvio just over one year. I've had uc for many years and other meds helped for a while. Then I was put on another and another and each one helped some but really did not satisfy. Sort of hit and miss.
It took about two-three months before the full effect takes over but when it did it was like being re-born, not to get too religious but the effect must be similar. I can do all the things I couldn't do before and everything, to this point, seems like a prayer's answer. Of course, this is my experience and I cannot say everyone will benefit but I would certainly suggest one try it. Also, no side effects of which I'm aware.
After taking so many meds previously and suffering side effects from them, it might be worth a try.

Long overdue relief! Congrats! Make sure to make the most of it

I've been on Entyvio for over a year. It has been the biggest difference maker medication wise so far for me. I started seeing positive signs during the loading dosages in the first 4-8 weeks. For many people, the timing they see results varies, I believe it can take a while before it starts to work so you and your GI will have to be patient with it potentially.

It hasn't put me in remission on its own so my GI and I are looking for the right medication to go along with it. I have felt no serious side effects, probably the only thing is being tired the 24 hours after getting an infusion, but that has gotten better as i get more infusions.

i would highly recommend it, the infusions are annoying to go to, but if it works then they are well worth it.