https://www.ctvnews.ca/health/cannabis-oil-improves-crohn-s-disease-symptoms-study-1.4141890I'll post on this side to as it's really interesting. Would like to see them do a trial for UC as well.
For any interested - It was only 8 weeks, so I would be curious of longer term. However it was the 'had no effect on gut inflammation' that I found intriguing. I'm curious how you can achieve 'clinical remission' without any improvements in endoscopic scores or in the inflammatory markers as they put it... if anyone comes across the study please post.
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From the article:
"Dr. Naftali, whose study is being billed as the first of its kind, found that an eight-week treatment with cannabis oil containing a four to one CBD to THC ratio produced clinical remission in up to 65 per cent of individuals with Crohn’s disease."
"The randomized, placebo-controlled study involved 50 people with moderately severe forms of the disease. The group that received cannabis oil also reported significant improvements in their quality of life."
"Interestingly, however, cannabis was found to have no effect on the gut inflammation that underscores the disease. We have previously demonstrated that cannabis can produce measurable improvements in Crohn's disease symptoms but, to our surprise, we saw no statistically significant improvements in endoscopic scores or in the inflammatory markers we measured in the cannabis oil group compared with the placebo group," Dr. Naftali explained. "We know that cannabinoids can have profound anti-inflammatory effects but this study indicates that the improvement in symptoms may not be related to these anti-inflammatory properties."