An interesting read, haven't heard FMT mentioned much lately. This goes through the colonization of bacterium from FMT, who is colonized and in what abundance and talks about
dysbiosis. Interesting read for those interested in this nerdy kinda stuff.
"Fecal microbiota transplantation (FMT) aims to modify the intestinal microbiota composition and function of the recipients by transferring donor fecal suspension into the gastrointestinal tract of a recipient, and has become a promising method for manipulating the gut microbiota. Its successful application for the treatment of Clostridium difficile infection has inspired people to apply it to inflammatory bowel disease patients (8,9,10,11,12,13). However, this application is still in its early stages. According to a recent systematic review and meta-analysis, after minimizing publication bias, IBD patients who received FMT had a remission rate of only 36.2%: 22% for UC and 60.5% for CD (14)."
"We found that 3 days after FMT, 11 out of 15 recipients were in remission (3 out of 4 UC recipients; 8 out of 11 CD recipients). Generally, bacterial colonization was observed to be lower in CD recipients than in UC recipients at both species and strain levels. Furthermore, across species, different strains displayed disease-specific displacement advantages under two-disease status. Finally, most post-FMT species (> 80%) could be properly predicted (AUC > 85%) using a random forest classification model, with the gut microbiota composition and clinical parameters of pre-FMT recipients acting as factors that contribute to prediction accuracy"
https://febs.onlinelibrary.wiley.com/doi/pdf/10.1002/2211-5463.12744