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The first Crohn’s patient receives the Crohn’s MAP Vaccine

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Ulcerative Colitis
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Posted 9/25/2021 6:32 PM (GMT 0)
https://crohnsmapvaccine.com/first-crohns-patient-receives-crohns-map-vaccine/
Posted 9/26/2021 12:01 PM (GMT 0)
That's great! I hope it works. Is MAP only in Crohns or does it infect UC too?
Posted 9/26/2021 2:08 PM (GMT 0)

CCinPA said...
That's great! I hope it works. Is MAP only in Crohns or does it infect UC too?

“Will the Vaccine help Ulcerative Colitis?

‘Pure’ Ulcerative Colitis (UC) is a different disease to Crohn’s, even though many of the symptoms are similar. It is not caused by MAP but is thought to be an auto-immune disease, the trigger for which is still unknown. Crohn’s Disease is caused by MAP infection in a genetically susceptible individual. The latest diagnostic techniques detect MAP in approaching 100% of Crohn’s patients.

You can, however, get MAP superinfection in someone with UC, making the UC worse. It is also well-known that diagnostic uncertainty is a big problem in Inflammatory Bowel Disease (IBD)… so in someone mistakenly diagnosed with UC when it is actually Crohn’s disease, MAP will be the cause.

If you have UC, there are 3 ways in which the Vaccine could help:

It is pure UC. Anti-MAP vaccination would protect against secondary MAP infection.
It is UC but superimposed MAP infection is making it worse. Anti-MAP vaccination should improve symptoms.
It looks like UC but it is actually Crohn’s. The vaccine is designed to fix it…and if it works in humans as it does in cattle, it should do so.
The new MAP test currently being validated is a simple, smart test which can be done on blood samples or routine gut biopsies. It is highly accurate and quantitative and will help to dispel this kind of diagnostic uncertainty in IBD.”

https://crohnsmapvaccine.com/faq/
Posted 9/27/2021 6:26 AM (GMT 0)
This is very interesting, and I will certainly stay tuned for further developments. I have UC that my Gastro is starting to wonder about whether it might actually be Crohn's. I've never heard of MAP before, but as I say, it's very interesting.

I am slightly concerned when I look at the "about us" section of their website. It appears to be a "one man band" of a Crohn's specialist, his physician daughter, and whole lot of fundraisers and web support people. I have no experience and am not smart enough to know if this is typical for research like this, or not. It's definitely not a big operation with tons of money behind it. I hope it's not just wishful thinking.

Thanks for posting this - I'll definitely stay tuned.
Posted 10/3/2021 4:05 PM (GMT 0)
You’re welcome.
Posted 10/3/2021 7:45 PM (GMT 0)
For Sonvolt-- a lot of science research starts small-scale, including medical research. Crohn's was established as a distinct ailment by Dr. Burrell Crohn, affiliated with the Mt. Sinai Hospital in NYC during the last century. Later in the 1960s, a successor of his, Dr. Henry Janowitz, joined with fellow gastroenterologist Dr. Burton Korelitz of Lenox Hill Hospital in NYC, plus a few early fundraisers which included relatives of their IBD patients, to found the predecessor of the present CCFA. *** This is also true of the research on mRNA that finally led to the 1st vaccines against COVID-19! On the I'net one can read some interesting 2020+ interviews with Dr. Katalin Kariko, who discusses her 1980s early research on mRNA at a university in Hungary. (She has said that her late mother used to tease her often about spending 15-hour days in the lab by asking: "When are you getting the Nobel Prize?") Thereafter she continued her research in the USA, at Temple U. then at U. of Pa. in Philadelphia. Now she's also a V.P. for research at Bio-N-Tech in Germany. (Plus potential candidate for Nobel recognition.) / Old Hat (40+ yrs with left-sided UC; in remission taking Colazal)
Posted 10/4/2021 4:09 AM (GMT 0)
Very interesting - thanks for that insight!
Posted 10/4/2021 2:16 PM (GMT 0)
I'll be getting this MAP vaccine as soon as it's available. I tested positive for MAP about 5 years ago.

That's if this vax makes it to daylight. If it actually cures Crohn's patients, the pharmaceutical industry may move to block it, or financially acquire it and then bury it.

The entire study has been independently funded because all private funding was cut off. If this vaccine cures Crohn's patients then it proves that MAP causes Crohn's and that MAP in the food supply (meat and milk) may be driving a Crohn's epidemic. That would implicate the agriculture industry.
Posted 10/4/2021 9:54 PM (GMT 0)
I find this very interesting.
I'm officially diagnosed with UC but I've always had a gut (no pun intended) feeling my UC is caused by a bacteria of some shape or form. My reason for thinking like this is when I was diagnosed I was prescribed Flagyl (Metronidazole) and budesonide for 2 weeks, in those 2 I went from pancolitis to 90 percent reduction of symptoms and was in full remission for the next 2 years on no more than 2g of Pentasa.
I felt so much better after the initial 2 week treatment that I naively thought I'd been cured and was taken aback when I went to my follow up consultation with my GI and she explained that I had UC and it was a lifelong condition.
Posted 10/7/2021 4:39 AM (GMT 0)
I tend to believe that Crohn's is caused by a bacteria. I was perfectly healthy until I developed food poisoning.... And it escalated to Crohn's Disease.

If this vaccine does work I too fear that it won't see the light of day. Too many large corporations would lose money, and the agricultural businesses would not want anyone to think they could develop Crohn's because of tainted meat or milk. I think that's part of the reason the good doctor and his daughter tried to have some type of control.

I am praying that it works.
Posted 10/7/2021 2:38 PM (GMT 0)
I always think about h.pylori and stomach ulcers and the fight that took to get it recognized as the cause. Seems coincidental that a bacterium can cause ulcers in the stomach lining — and that UC and crohns are characterized by ulcers in the lining of the intestines.

Anyway it was eventually accepted that stomach ulcers aren’t caused by stress so hopefully the same thing will happen here if they are able to eventually identify a cause.
Posted 12/5/2021 12:30 PM (GMT 0)
https://crohnsmapvaccine.com/obituary-professor-john-hermon-taylor/
Posted 12/5/2021 1:47 PM (GMT 0)
Oh no that is sad news 😭
What will happen with the trial now?
Posted 12/5/2021 3:44 PM (GMT 0)
It continues.
Posted 1/27/2022 4:31 PM (GMT 0)

Somebody said...
the guy who was the first Crohn’s patient to receive a low dose of the anti map vaccine has posted an update in Facebook. He says he is only one person and cannot draw any conclusions yet but he is now averaging 2 BMs a day and getting to the loo in time which is better than before and this has lasted a few months.
…
He’s in group 1 as I understand it which means half dose of vaccine 1
There are 5 groups altogether the 5th ones get full dose of both jabs if all gone well in the earlier lower dose groups
This has been a slow moving project for a long time it was one retired gastro professor working on shoestring budget and a theory
He sadly passed away earlier this year
Other experts were sufficiently interested in his ideas to get involved and take over the project.
His daughter who is a GP I think posts occasional updates on a Crohn’s map vaccine Facebook group which is where I saw Sean’s progress post
He is saying “cautiously optimistic” but obviously doesn’t know how the other guinea pigs have responded
Worth keeping an eye on is my view

https://crohnsforum.com/threads/crohn’s-map-vaccine.86340/#post-1041824
Posted 1/27/2022 9:13 PM (GMT 0)
thanks for keeping us updated on this!
Posted 2/5/2022 12:03 AM (GMT 0)
So the FDA approve it yet? Is it approved by authorities yet? If not? When it will be available? And schedule for this?
Posted 2/5/2022 9:36 AM (GMT 0)

FlowersGal said...
I always think about h.pylori and stomach ulcers and the fight that took to get it recognized as the cause. Seems coincidental that a bacterium can cause ulcers in the stomach lining — and that UC and crohns are characterized by ulcers in the lining of the intestines.

Anyway it was eventually accepted that stomach ulcers aren’t caused by stress so hopefully the same thing will happen here if they are able to eventually identify a cause.


I’ve had h.pylori? Do you think there is a connection
Posted 2/5/2022 6:57 PM (GMT 0)
I want this vaccine.
Posted 2/15/2022 2:59 PM (GMT 0)
"Trial update and a call for volunteers!"
https://twitter.com/crohnsvaccine/status/1493530609565802498
Posted 2/15/2022 5:06 PM (GMT 0)
Thanks for the update. Only open to people with Crohn's in the U.K. who aren't on any immunomodulators.
Posted 2/16/2022 6:09 PM (GMT 0)
This offers real hope to people with Crohn's who are languishing with no alternatives for recovery.
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