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Mesalamine suppositories

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Posted 9/2/2022 10:48 PM (GMT 0)
I was prescribed mesalamine suppositories for my current UC flare. I have taken oral mesalamine for years. The info on the suppositories indicates to avoid prolonged exposure to direct and/or artificial sunlight. Does anyone know anything about this? I never got a call back from my doctor today about this question. I’ve never heard about that with the oral mesalamine, but I may have missed it. Is there more of a concern with the suppository for some reason?
Posted 9/2/2022 11:39 PM (GMT 0)
I never heard of that before. I used the enemas, not the suppositories, but don't know why a suppository would be different. Maybe someone else will stop by with more info.

In the meantime .... slather on the sunscreen smile
Posted 9/3/2022 2:28 AM (GMT 0)
Do they mean the patient should avoid excessive sunlight? Or keep the suppository out of the sun? That would make sense based on the usual color change that happens with the off-white enemas.
Posted 9/3/2022 2:46 AM (GMT 0)
It means the person. The fine print in the box talks about photosensitivity of the individual and tells you to avoid sun exposure, wear protective clothing, and use sunscreen. It also talks about increased photosensitivity for people with skin conditions. I’ve never heard that about the oral mesalamine, but I’ve never looked for it.
Posted 9/4/2022 3:10 AM (GMT 0)
Ooops....ive been on oral for 20 years, occasional enemas and suppositories. I am a sun worshipper...of course using plenty of sunscreen. It just makes me feel better, and a great break from 6 months of dark rainy months a year.
Posted 9/8/2022 4:54 AM (GMT 0)
I was going to say maybe because it will melt? Lol. I've been on mesalamine (oral and rectal) since 2007 and I don't avoid the sun.
Posted 9/22/2022 8:27 PM (GMT 0)
I've been on Salofalk suppositories for 7 years, and I never had a problem with sunlight. The instructions on my suppositories don't mention anything about avoiding sunlight. However it is listed under "Rare Side Effects: Increased skin sensitivity to sunlight and UV light (photosensitivity)". It's probably nothing to worry about unless you have other skin conditions.
Posted 9/22/2022 11:52 PM (GMT 0)
My Lialda script mentions limiting sun exposure and my GI said the same thing. Wearing a hat and sunscreen is recommended. I seem to burn more easily on 5-ASA myself. Never heard that advice for supps but it may be that any mesalamine form can contribute to sunburn.
Posted 9/24/2022 7:46 PM (GMT 0)
I had a photosensitive reaction not long after being diagnosed. I was on Apriso at the time and my GI freaked out that the reaction was from it. My reaction was a horrible itchy rash on my arms and legs mostly. They gave me a steroid cream but that didn’t touch the itching. It finally went away and I never got it back, even though I stayed on Apriso. Later I decided it might have been from an antidepressant I was taking at the time.
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