PLEASE - Yes, Rowasa is the brand name in the US (and maybe other places?) for mesalamine rectal suspension enemas. Your daughter must have the generic. They are supposed to be the same ingredients, but the brand name one seems to work better for some here. I have never had the actual Rowasa, just the generic ones, but the generic bottles are kind of cheaply made and I've heard the actual Rowasa ones are a bit easier to administer. And, yes, they can be hard to retain, especially in one is quite inflamed. It took me a while to get it down, and it is still hard sometimes, but usually the urge to expel the enema passes after a few minutes. And the urge lessens for me as my inflammation goes down. Your daughter can also try squeezing any air out of the bottle before she uses them. This seems to make them easier to retain. Just be careful not to squeeze too hard and have the actual medication come out! =)